Elian M
Department of Clinical Neurophysiology, Oldchurch Hospital, Romford, Essex, UK.
J Neurol Neurosurg Psychiatry. 1991 Oct;54(10):927-8. doi: 10.1136/jnnp.54.10.927.
The ability to identify smells was tested in nine males and six females with motor neuron disease (MND) of varying severity, using the University of Pennsylvania Smell Identification Test (UPSIT). The olfactory impairment found in MND patients compared with age and sex matched controls is statistically significant at the 0.005 level. The relationship with Parkinson's disease, with Alzheimer's dementia and the possible aetiological implications of this new aspect of the MND are discussed.
使用宾夕法尼亚大学嗅觉识别测试(UPSIT),对9名男性和6名患有不同严重程度运动神经元疾病(MND)的女性进行了嗅觉识别能力测试。与年龄和性别匹配的对照组相比,MND患者中发现的嗅觉障碍在0.005水平上具有统计学意义。本文讨论了MND这一新情况与帕金森病、阿尔茨海默病痴呆症的关系以及可能的病因学意义。