用于检测泌尿生殖系统标本中沙眼衣原体的化学发光免疫分析法和直接免疫荧光试验的评估
Evaluation of a chemiluminometric immunoassay and a direct immunofluorescence test for detecting Chlamydia trachomatis in urogenital specimens.
作者信息
Neman-Simha V, Delmas-Beauvieux M C, Geniaux M, Bébéar C
机构信息
Laboratoire de Bactériologie, Hôpital Pellegrin, Bordeaux, France.
出版信息
Eur J Clin Microbiol Infect Dis. 1991 Aug;10(8):662-5. doi: 10.1007/BF01975822.
A new chemiluminometric immunoassay (Magic Lite) and a direct immunofluorescence technique (MicroTrak) were compared with cell culture in the diagnosis of Chlamydia trachomatis infections. Both assays were evaluated using 260 genital specimens (89 men, 171 women), 26 of which were culture positive. The respective sensitivity of the chemiluminometric immunoassay and immunofluorescence technique was 88.5% and 84.6%, the specificity 97% and 99.6%, the positive predictive value 76.7% and 95.6%, and the negative predictive value 98.7% and 98.3%. Both methods could serve as an alternative to culture in the diagnosis of urogenital chlamydial infections.
将一种新的化学发光免疫分析法（Magic Lite）和直接免疫荧光技术（MicroTrak）与细胞培养法进行比较，以诊断沙眼衣原体感染。使用260份生殖器标本（89名男性，171名女性）对这两种检测方法进行评估，其中26份标本细胞培养呈阳性。化学发光免疫分析法和免疫荧光技术各自的敏感性分别为88.5%和84.6%，特异性分别为97%和99.6%，阳性预测值分别为76.7%和95.6%，阴性预测值分别为98.7%和98.3%。在泌尿生殖系统衣原体感染的诊断中，这两种方法均可作为细胞培养法的替代方法。
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