Fang-Yen Christopher, Oh Seungeun, Park Yongkeun, Choi Wonshik, Song Sen, Seung H Sebastian, Dasari Ramachandra R, Feld Michael S
G.R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Opt Lett. 2007 Jun 1;32(11):1572-4. doi: 10.1364/ol.32.001572.
We describe a heterodyne Mach-Zehnder interferometric microscope capable of quantitative phase imaging of biological samples with subnanometer sensitivity and frame rates up to 10 kHz. We use the microscope to image cultured neurons and measure nanometer-scale voltage-dependent motions in cells expressing the membrane motor protein prestin.
我们描述了一种外差马赫曾德尔干涉显微镜，它能够对生物样品进行定量相位成像，灵敏度可达亚纳米级，帧率高达10千赫兹。我们使用该显微镜对培养的神经元进行成像，并测量表达膜运动蛋白prestin的细胞中纳米级的电压依赖性运动。
