Badaruddin Denise H, Andrews Glena L, Bölte Sven, Schilmoeller Kathryn J, Schilmoeller Gary, Paul Lynn K, Brown Warren S
The Travis Research Institute, Center for Biopsychosocial Research, Fuller Graduate School of Psychology, 180 N. Oakland Ave, Pasadena, CA 91101, USA.
Child Psychiatry Hum Dev. 2007 Dec;38(4):287-302. doi: 10.1007/s10578-007-0065-6. Epub 2007 Jun 13.
Archival data from a survey of parent observations was used to determine the prevalence of social and behavioral problems in children with agenesis of the corpus callosum (ACC). Parent observations were surveyed using the Child Behavior Checklist (CBCL) for 61 children with ACC who were selected from the archive based on criteria of motor development suggesting a relatively high general level of functioning. Younger children with ACC (ages 2-5) were rated as primarily having problems with sleep. Older children with ACC (ages 6-11) manifested problems in attention, social function, thought, and somatic complaints. The older children with ACC were also compared to CBCL data from 52 children with autism who were selected from a previous study. Children with ACC were generally less impaired than children with autism on nearly all scales, with significantly less severe problems in the areas of attention, anxiety/depression, social function, and unusual thoughts. A further questionnaire related to diagnostic criteria for autism indicated that some children with ACC had traits that are among those that contribute to the diagnosis of autism within the domains of social interaction and social communication, but fewer who manifest repetitive and restricted behaviors.
一项关于家长观察的调查的存档数据被用于确定胼胝体发育不全（ACC）儿童的社会和行为问题的患病率。使用儿童行为检查表（CBCL）对61名ACC儿童的家长观察进行了调查，这些儿童是根据运动发育标准从存档中挑选出来的，表明其总体功能水平相对较高。年龄较小的ACC儿童（2至5岁）主要被评为存在睡眠问题。年龄较大的ACC儿童（6至11岁）在注意力、社交功能、思维和躯体不适方面表现出问题。还将年龄较大的ACC儿童与之前一项研究中挑选出的52名自闭症儿童的CBCL数据进行了比较。在几乎所有量表上，ACC儿童的受损程度通常都低于自闭症儿童，在注意力、焦虑/抑郁、社交功能和异常思维等方面的问题明显不那么严重。一份与自闭症诊断标准相关的进一步问卷表明，一些ACC儿童具有在社交互动和社交沟通领域有助于自闭症诊断的特征，但表现出重复和受限行为的儿童较少。
