Belicová A, Krzková L, Krajcovic J, Jurkovic D, Sojka M, Ebringer L, Duinský R
Institute of Cell Biology, Faculty of Science, Comenius University, 842 15 Bratislava, Slovakia.
Folia Microbiol (Praha). 2007;52(2):115-9. doi: 10.1007/BF02932149.
Three hundred and ten enterococcal isolates (178 Enterococcus faecium, 68 E. durans, 49 E. faecalis, 8 E. italicus, 3 E. gallinarum, 3 E. casseliflavus, and 1 E. hirae) from Slovak Bryndza cheese were evaluated for susceptibility to nine antimicrobial agents (vancomycin, teicoplanin, ampicillin, streptomycin, gentamicin, erythromycin, rifampicin, nitrofurantoin, and ciprofloxacin). All enterococcal isolates from Bryndza cheese were susceptible to ampicillin, streptomycin, gentamicin, vancomycin, and teicoplanin as determined by the disk diffusion method. Vancomycin resistance genes vanA and vanB were not detected. Resistance rates of enterococcal isolates to rifampicin, erythromycin, ciprofloxacin, and nitrofurantoin were 24, 26, 2, and 1 %, respectively. Thirty-six % of E. faecium isolates and 22 % of the E. faecalis isolates were resistant to erythromycin. Resistance to rifampicin was similar in E. faecium (31 %) and E. faecalis (29 %). Both E. faecium and E. faecalis strains showed the same resistance to ciprofloxacin (2 %). E. durans isolates showed low levels of resistance to rifampicin, erythromycin, ciprofloxacin, and nitrofurantoin (1-4 %). Forty-eight (30 %) of the E. faecium isolates, two (3 %) of the E. durans isolates, and six (12 %) of the E. faecalis isolates exhibited multidrug resistance. The highest frequency of resistant enterococci was observed in Bryndza produced in winter season.
对来自斯洛伐克布伦扎奶酪的310株肠球菌分离株（178株屎肠球菌、68株耐久肠球菌、49株粪肠球菌、8株意大利肠球菌、3株鹑鸡肠球菌、3株格氏肠球菌和1株海氏肠球菌）进行了9种抗菌药物（万古霉素、替考拉宁、氨苄西林、链霉素、庆大霉素、红霉素、利福平、呋喃妥因和环丙沙星）的药敏试验。采用纸片扩散法测定，布伦扎奶酪中的所有肠球菌分离株对氨苄西林、链霉素、庆大霉素、万古霉素和替考拉宁均敏感。未检测到万古霉素耐药基因vanA和vanB。肠球菌分离株对利福平、红霉素、环丙沙星和呋喃妥因的耐药率分别为24%、26%、2%和1%。36%的屎肠球菌分离株和22%的粪肠球菌分离株对红霉素耐药。屎肠球菌（31%）和粪肠球菌（29%）对利福平的耐药情况相似。屎肠球菌和粪肠球菌菌株对环丙沙星的耐药率相同（2%）。耐久肠球菌分离株对利福平、红霉素、环丙沙星和呋喃妥因的耐药水平较低（1%-4%）。48株（30%）屎肠球菌分离株、2株（3%）耐久肠球菌分离株和6株（12%）粪肠球菌分离株表现出多重耐药性。在冬季生产的布伦扎奶酪中观察到耐药肠球菌的频率最高。
