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瑞典一所高中青少年的服药行为及药物相关问题

Medicine-taking behaviour and drug-related problems in adolescents of a Swedish high school.

作者信息

Westerlund Michael, Brånstad Jan-Olof, Westerlund Tommy

机构信息

Olympiaskolan, Helsingborg, Sweden.

出版信息

Pharm World Sci. 2008 Jun;30(3):243-50. doi: 10.1007/s11096-007-9168-1. Epub 2007 Nov 6.

Abstract

OBJECTIVES

To examine (1) which over-the-counter (OTC) and prescription drugs adolescents most frequently use and for which ailments or diseases, and (2) which DRPs adolescents have experienced, as well as if and by whom these problems were resolved. Setting A high school in Helsingborg, Sweden.

METHODS

A self-completion questionnaire was designed and used in students with a median age of 17 in late 2005 and early 2006. To enable students to identify DRPs they may have experienced, the questionnaire contained a list of DRPs in lay language. The questionnaires were distributed by the teachers to be completed by the students in the classroom.

MAIN OUTCOME MEASURES

Self-reported prevalence of OTC and prescription drug use and experienced drug-related problems.

RESULTS

A total of 245 students (99%) took part, 138 females and 107 males. OTCs had been used occasionally by 37.7% of the girls and 62.6% of the boys, while 10.9% and 6.5% respectively were daily users. Analgesics were the most frequently used OTCs. DRPs had been experienced by 31.1% of the female and 19.6% of the male students, the most common of which was therapy failure (too little or no effect), accounting for 46.5% of the girls' and 38.1% of the boys' OTC DRPs. Eighty-five percent of the problems with OTCs had been resolved, half of them by the teenagers themselves. Prescription drugs had been used occasionally by 31.9% of the female and 29.0% of the male students, while 28.3% and 26.2% respectively reported using such drugs on a daily basis. Antibiotics were the most frequently taken prescription drugs. DRPs related to prescribed drugs were reported by 32.6% of the girls and 10.3% of the boys. The most common DRPs were side effects, accounting for 34.8% of the girls' problems, and therapy failure, experienced by 28.6% of the boys. All the boys' DRPs were reported to be resolved, but only 75% of those of the girls. Physicians were stated to have resolved the problems in 41.4% of the cases.

CONCLUSIONS

There is a need to develop the interface between pharmacy practitioners and adolescents, as the study has demonstrated frequent use of OTCs and prescription drugs as well as a high prevalence of DRPs in adolescents. The reasons for therapy failure, which was the most common problem, should be further explored and measures taken by pharmacists and physicians to minimise it.

摘要

目的

研究(1)青少年最常使用的非处方药(OTC)和处方药及其用于治疗的疾病,(2)青少年经历过的药物相关问题(DRP),以及这些问题是否得到解决及由谁解决。研究地点为瑞典赫尔辛堡的一所高中。

方法

设计了一份自填式问卷,并于2005年末和2006年初在中位年龄为17岁的学生中使用。为使学生能够识别他们可能经历过的DRP,问卷中用通俗易懂的语言列出了一系列DRP。问卷由教师分发,学生在课堂上完成。

主要观察指标

自我报告的OTC和处方药使用情况及经历过的药物相关问题。

结果

共有245名学生(99%)参与,其中女生138名,男生107名。37.7%的女生和62.6%的男生偶尔使用OTC,而每日使用者分别为10.9%和6.5%。镇痛药是最常使用的OTC。31.1%的女生和19.6%的男生经历过DRP,其中最常见的是治疗失败(效果不佳或无效果),占女生OTC DRP的46.5%,男生的38.1%。85%的OTC问题已得到解决,其中一半由青少年自己解决。31.9%的女生和29.0%的男生偶尔使用处方药,而分别有28.3%和26.2%的人报告每天使用此类药物。抗生素是最常服用的处方药。32.6%的女生和10.3%的男生报告了与处方药相关的DRP。最常见的DRP是副作用,占女生问题的34.8%,28.6%的男生经历过治疗失败。据报告,所有男生经历的DRP都已得到解决,但女生中只有75%的问题得到解决。41.4%的案例表明问题是由医生解决的。

结论

由于该研究表明青少年频繁使用OTC和处方药以及DRP的高发生率,因此有必要改善药剂师与青少年之间的沟通。治疗失败是最常见的问题,应进一步探究其原因,并由药剂师和医生采取措施将其降至最低。

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