Zong Zhiyong, Lü Xiaoju, Valenzuela Jubelle K, Partridge Sally R, Iredell Jon
Department of Infectious Diseases, West China Hospital, Sichuan University, Chengdu, China.
Int J Antimicrob Agents. 2008 Jan;31(1):50-4. doi: 10.1016/j.ijantimicag.2007.08.019.
Twenty-two non-repetitive carbapenem-resistant Acinetobacter baumannii isolates were obtained from Intensive Care Unit patients. All of the isolates carried bla(OXA-23), bla(OXA-66), a novel cephalosporinase-encoding gene (bla(ADC-25)) and a class 1 integron with an aacC1-orfP-orfQ-aadA1a cassette array and had identical enterobacterial repetitive intergenic consensus (ERIC) profiles. ISAba1 was found upstream of bla(OXA-23), but was not associated with bla(OXA-66) or bla(ADC-25).
从重症监护病房患者中获得了22株非重复的耐碳青霉烯鲍曼不动杆菌分离株。所有分离株均携带bla(OXA - 23)、bla(OXA - 66)、一个新的头孢菌素酶编码基因(bla(ADC - 25))以及一个带有aacC1 - orfP - orfQ - aadA1a盒式阵列的1类整合子，并且具有相同的肠杆菌重复基因间共识(ERIC)图谱。ISAba1位于bla(OXA - 23)上游，但与bla(OXA - 66)或bla(ADC - 25)无关。
