Showalter Shayna L, Hager Eric, Yeo Charles J
Department of Surgery, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Semin Oncol. 2008 Apr;35(2):160-71. doi: 10.1053/j.seminoncol.2007.12.008.
Isolated metastases to the pancreas and spleen are a rare occurrence. When they are diagnosed, pancreatic metastases are most often from renal cell carcinoma, lung cancer, and breast cancer. The most common source of splenic metastases is gynecological in origin; the overwhelming majority is ovarian. If extensive staging studies reveal these metastases to be isolated, then curative resection may be warranted. This review will demonstrate that long-term survival may be achieved in patients with isolated metastases and a prolonged disease-free interval.
胰腺和脾脏的孤立性转移很少见。当诊断出这些转移时，胰腺转移最常见于肾细胞癌、肺癌和乳腺癌。脾转移最常见的来源是妇科疾病；绝大多数是卵巢癌。如果广泛的分期研究显示这些转移是孤立性的，那么可能有必要进行根治性切除。这篇综述将表明，孤立性转移且无病间期延长的患者可能实现长期生存。
