Sharafkhaneh Amir, Falk Jeremy A, Minai Omar A, Lipson David A
Division of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Proc Am Thorac Soc. 2008 May 1;5(4):438-41. doi: 10.1513/pats.200708-130ET.
This article reviews management strategies that may improve the outcome of thoracic surgery and particularly lung volume reduction surgery (LVRS) in patients with severe emphysema. Maximal preoperative pharmacologic therapy includes bronchodilators and inhaled corticosteroids to attain peak lung function at the time of surgery. Nonpharmacologic measures include smoking cessation and pulmonary rehabilitation. Mechanical ventilation during the perioperative period should ensure adequate oxygenation, while avoiding dynamic hyperinflation. Keys to successful postoperative care include close monitoring while in the intensive care unit, early extubation, adequate pain control, chest physiotherapy and appropriate chest tube management. Aggressive management of early postoperative complications, including air leaks, respiratory failure, arrhythmias, and hemorrhage, can also be expected to improve outcomes.
本文综述了可能改善胸外科手术,尤其是重度肺气肿患者肺减容手术(LVRS)预后的管理策略。术前最大程度的药物治疗包括使用支气管扩张剂和吸入性皮质类固醇,以在手术时达到最佳肺功能。非药物措施包括戒烟和肺康复。围手术期的机械通气应确保充分的氧合,同时避免动态肺过度充气。术后成功护理的关键包括在重症监护病房密切监测、早期拔管、充分的疼痛控制、胸部物理治疗和适当的胸管管理。积极处理术后早期并发症,包括漏气、呼吸衰竭、心律失常和出血,也有望改善预后。