Vilata Juan Jose, Varela José A, Olmos Luis, Colombo José A, Llorens María A, de los Terreros Miguel Sainz, Badía Xavier
Department of Dermatology, Consorcio Hospital General Universitario, Universidad de Valencia, Gijón, Spain.
Acta Derm Venereol. 2008;88(3):257-62. doi: 10.2340/00015555-0422.
The aim of this validation study was to assess the measurement properties of the CECA (Spanish acronym for the Specific Questionnaire for Condylomata Acuminata) in patients with anogenital condylomas. A total of 247 patients aged > 18 years completed the questionnaire on 2 occasions as well as the Dermatology Life Quality Index (DLQI). The CECA questionnaire showed good internal consistency (Cronbach's alpha values of 0.86 and 0.91 in the emotional and sexual activity dimensions) and good testretest reliability (intraclass correlation coefficient 0.76 emotional dimension, 0.82 sexual activity dimension). Patients with de novo lesions and those with more extensive lesions and larger number of warts showed poorer health-related quality of life. CECA and DLQI scores correlated moderately. Patients whose lesions cleared at follow-up or with a reduction of >or= 50% showed a better improvement of health-related quality of life. The CECA questionnaire is a valid, reliable and sensitive tool for the assessment of health-related quality of life in patients with anogenital warts.
这项验证性研究的目的是评估CECA（尖锐湿疣特异性问卷的西班牙语首字母缩写）在肛门生殖器疣患者中的测量特性。共有247名年龄大于18岁的患者分两次完成了该问卷以及皮肤病生活质量指数（DLQI）。CECA问卷显示出良好的内部一致性（情感维度和性活动维度的Cronbach's α值分别为0.86和0.91）和良好的重测信度（组内相关系数，情感维度为0.76，性活动维度为0.82）。初发性病变患者、病变范围更广和疣体数量更多的患者健康相关生活质量较差。CECA和DLQI评分呈中度相关。随访时病变清除或减少≥50%的患者健康相关生活质量改善更好。CECA问卷是评估肛门生殖器疣患者健康相关生活质量的有效、可靠且敏感的工具。
