Collins R J, Cheung A, Ngan H Y, Wong L C, Chan S Y, Ma H K
Department of Obstetrics and Gynaecology, University of Hong Kong.
Arch Gynecol Obstet. 1991;248(3):139-43. doi: 10.1007/BF02390091.
A rare case of mixed carcinoma of ovary with a predominant malignant neuroendocrine and a lesser mucinous tumor component is described. Extensive areas of enteric-type epithelium containing endocrine cells were present in both the mucinous borderline tumor element and in the small foci of mucinous adenocarcinoma. Transition from the mucinous tumor to the malignant neuroendocrine component provides evidence for the derivation of some neuroendocrine or carcinoid tumors direct from mucinous tumors without necessarily being a component of a teratoma. Contrary to reported examples of mucinous carcinoid, the overgrowth and spread of the neuroendocrine component characterised the aggressive and lethal nature of this tumor.
本文描述了一例罕见的卵巢混合性癌，其主要成分为恶性神经内分泌肿瘤，黏液性肿瘤成分较少。在黏液性交界性肿瘤成分和黏液性腺癌小灶中均存在广泛的含有内分泌细胞的肠型上皮区域。从黏液性肿瘤向恶性神经内分泌成分的转变为一些神经内分泌肿瘤或类癌直接起源于黏液性肿瘤提供了证据，而不一定是畸胎瘤的组成部分。与报道的黏液性类癌病例相反，神经内分泌成分的过度生长和扩散是该肿瘤侵袭性和致死性的特征。
