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用高致病性禽流感病毒(H5N1)对牛进行实验性感染。

Experimental infection of cattle with highly pathogenic avian influenza virus (H5N1).

作者信息

Kalthoff Donata, Hoffmann Bernd, Harder Timm, Durban Markus, Beer Martin

机构信息

Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

出版信息

Emerg Infect Dis. 2008 Jul;14(7):1132-4. doi: 10.3201/eid1407.071468.

Abstract

Four calves were experimentally inoculated with highly pathogenic avian influenza virus A/cat/Germany/R606/2006 (H5N1) isolated from a cat in 2006. All calves remained healthy, but several animals shed low amounts of virus, detected by inoculation of nasal swab fluid into embryonated chicken eggs and onto MDCK cells. All calves seroconverted.

摘要

对四头小牛进行了实验性接种,接种的是2006年从一只猫身上分离出的高致病性甲型禽流感病毒A/猫/德国/R606/2006(H5N1)。所有小牛均保持健康,但通过将鼻拭子液体接种到鸡胚和MDCK细胞上检测到,有几只动物排出少量病毒。所有小牛都发生了血清转化。

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