为患有特纳综合征的女儿未来可能的使用而对母亲的卵母细胞进行冷冻保存：病例报告。
Cryopreservation of a mother's oocytes for possible future use by her daughter with Turner syndrome: case report.
作者信息
Gidoni Yariv S, Takefman Janet, Holzer Hananel E G, Elizur Shai E, Son Weon-Young, Chian Ri-Cheng, Tan Seang Lin
机构信息
Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, McGill Reproductive Center, McGill University Health Center, Montreal, Quebec, Canada.
出版信息
Fertil Steril. 2008 Nov;90(5):2008.e9-12. doi: 10.1016/j.fertnstert.2008.05.050. Epub 2008 Aug 9.
OBJECTIVE
To report a new fertility alternative for women with Turner syndrome, who are rendered infertile, by having their mothers freeze their own oocytes for the purpose of donating to their daughters when they are adults.
DESIGN
Case report.
SETTING
Academic teaching hospital.
PATIENT(S): A 33-year-old healthy mother of three children; and her second child, a 6-year-old daughter recently diagnosed with Turner syndrome.
INTERVENTION(S): Mother-to-daughter oocyte donation combined with oocyte vitrification.
MAIN OUTCOME MEASURE(S): Number of cryopreserved oocytes.
RESULT(S): After three cycles of ovarian stimulation, 30 oocytes were cryopreserved for the daughter's possible future use.
CONCLUSION(S): The treatment option presented here opens the door for the banking of a mother's oocytes as a possible donation to a young daughter with a medical condition that leads to infertility, for her possible future use.
目的
报告一种为患有特纳综合征而不育的女性提供的新的生育选择，即让她们的母亲冷冻自己的卵母细胞，以便在女儿成年时捐赠给她们。
设计
病例报告。
地点
学术教学医院。
患者
一位育有三个孩子的33岁健康母亲；以及她的第二个孩子，一名最近被诊断患有特纳综合征的6岁女儿。
干预措施
母源性卵母细胞捐赠联合卵母细胞玻璃化冷冻。
主要观察指标
冷冻保存的卵母细胞数量。
结果
经过三个周期的卵巢刺激，共冷冻保存了30个卵母细胞，以备女儿未来可能使用。
结论
此处提出的治疗方案为储存母亲的卵母细胞打开了大门，这些卵母细胞有可能捐赠给患有导致不育的疾病的年幼女儿，供其未来可能使用。
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