Golli V, Eliescu A
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1976 Jul-Sep;25(3):147-51.
A total of 2057 children, from a village with an isolated farm of tuberculous cattle have been classified in the following groups: A--1843 children from healthy families; B--140 children whose parents were working at the bovine farm; C--70 tb contacts, and D--4 children with parents working at the farm and relatives suffering with tuberculosis. All were skin tested simultaneously with 1 and 10 PPD units. Milk was brought home from the farm by those who worked there, that was used without boiling. A total of 14,5% of all the children had a reaction of more than 5 mm to one PPD unit. The percentages were of 8,4 in group A 52,1 in group B and 94,3 in group C (P less than 0,001). Incidence of more than 9 mm reactions was of 5% in group A, 45% in group B and 91,4% in group C (P less than 0,001). The mean diameter for one PPD unit was of 1,1 mm in group A, 7,58 mm in group B and 15,88 mm in group C (P less than 0,001). The major risk factor is represented by the tuberculous patients, but use of milk, or of milk derivatives from diseased cattle could also be incriminated. Synchronous neutralization of these two sources of contamination remains the primary action to be carried out for the prevention of the tuberculous infection dissemination.
来自一个有患结核病奶牛隔离养殖场的村庄的2057名儿童被分为以下几组：A组——来自健康家庭的1843名儿童；B组——父母在奶牛场工作的140名儿童；C组——70名结核病接触者；D组——父母在农场工作且亲属患有结核病的4名儿童。所有人同时用1个和10个结核菌素单位进行皮肤测试。在奶牛场工作的人把牛奶从农场带回家，未经煮沸就饮用。所有儿童中共有14.5%对1个结核菌素单位的反应超过5毫米。A组的比例为8.4%，B组为52.1%，C组为94.3%（P小于0.001）。反应超过9毫米的发生率在A组为5%，B组为45%，C组为91.4%（P小于0.001）。1个结核菌素单位的平均直径在A组为1.1毫米，B组为7.58毫米，C组为15.88毫米（P小于0.001）。主要危险因素是结核病患者，但使用患病奶牛的牛奶或奶制品也可能是罪魁祸首。同时消除这两种污染源仍然是预防结核感染传播要采取的首要行动。
