HARDY P H, HORSFALL F L
J Exp Med. 1948 Oct 1;88(4):463-84. doi: 10.1084/jem.88.4.463.
Evidence is presented which shows that there is a component present in normal allantoic fluid, probably mucoprotein in nature, capable of combining with influenza A virus (PR8), and that following combination between this component and the virus only partial dissociation of the complex occurs. Evidence is also presented which strongly suggests that the component is present in virus-infected allantoic fluid in which it is in part combined with the virus and in part free although altered by viral action. The probability that the component is present as well in highly purified preparations of influenza virus, and its effect upon various reactions obtained with this agent are discussed.
有证据表明,正常尿囊液中存在一种成分,其本质可能是粘蛋白,能够与甲型流感病毒(PR8)结合,并且该成分与病毒结合后,复合物仅发生部分解离。还有证据强烈表明,该成分存在于病毒感染的尿囊液中,在其中它部分与病毒结合,部分游离,尽管因病毒作用而发生了改变。文中还讨论了该成分也存在于流感病毒高度纯化制剂中的可能性,以及它对用该制剂获得的各种反应的影响。