补体介导的针对人类7号染色体编码抗原的抗血清细胞毒性反应：人-鼠体细胞杂种中重排的人类7号染色体的免疫选择
Complement-mediated antiserum cytotoxic reactions to human chromosome 7 coded antigen(s): immunoselection of rearranged human chromosome 7 in human-mouse somatic cell hybrids.
作者信息
Knowles B B, Solter D, Trinchieri G, Maloney K M, Ford S R, Aden D P
出版信息
J Exp Med. 1977 Feb 1;145(2):314-26. doi: 10.1084/jem.145.2.314.
Abstract
Immunoselection via complement-dependent lysis of human-mouse somatic cell hybrids containing chromosome 7, with antisera reactive to cell surface antigen(s) coded for by chromosome 7, has resulted in growth of somatic cell hybrids containing rearranged human chromosome 7s. Investigation of these hybrids has localized the gene(s) coding for the relevant cell surface antigen(s) to the short arm of human chromosome 7. The simian virus 40 integration site and the gene coding for human beta-glucuronidase appear to be localized to the long arm of chromosome 7 in this hybrid clone.
摘要
通过对含有7号染色体的人-鼠体细胞杂种进行补体依赖裂解的免疫选择，利用与7号染色体编码的细胞表面抗原发生反应的抗血清，已获得了含有重排人7号染色体的体细胞杂种的生长。对这些杂种的研究已将编码相关细胞表面抗原的基因定位到人类7号染色体的短臂上。在这个杂种克隆中，猿猴病毒40整合位点和编码人β-葡萄糖醛酸酶的基因似乎定位在7号染色体的长臂上。
相似文献
1
Complement-mediated antiserum cytotoxic reactions to human chromosome 7 coded antigen(s): immunoselection of rearranged human chromosome 7 in human-mouse somatic cell hybrids.补体介导的针对人类7号染色体编码抗原的抗血清细胞毒性反应：人-鼠体细胞杂种中重排的人类7号染色体的免疫选择
J Exp Med. 1977 Feb 1;145(2):314-26. doi: 10.1084/jem.145.2.314.
2
3
Tumorigenicity of mouse-human diploid hybrids in nude mice.小鼠 - 人二倍体杂种在裸鼠中的致瘤性。
Science. 1975 Dec 19;190(4220):1200-2. doi: 10.1126/science.173020.
4
Assignment of the T-antigen gene of simian virus 40 to human chromosome C-7.将猴病毒40的T抗原基因定位于人类C-7染色体。
Proc Natl Acad Sci U S A. 1973 Dec;70(12):3617-20. doi: 10.1073/pnas.70.12.3617.
5
Genetics of cell transformation by simian virus 40.猿猴病毒40介导的细胞转化遗传学
Cold Spring Harb Symp Quant Biol. 1975;39 Pt 1:335-43. doi: 10.1101/sqb.1974.039.01.044.
6
Human beta-glucuronidase: assignment of the structural gene to chromosome 7 using somatic cell hybrids.人β-葡萄糖醛酸酶：利用体细胞杂种将结构基因定位于7号染色体
Biochem Genet. 1977 Apr;15(3-4):367-82. doi: 10.1007/BF00484467.
7
Concordant segregation of the expression of SV40 T antigen and human chromosome 7 in mouse-human hybrid subclones.小鼠 - 人杂交亚克隆中SV40 T抗原表达与人类7号染色体的一致分离。
J Exp Med. 1974 May 1;139(5):1350-3. doi: 10.1084/jem.139.5.1350.
8
Reversion in hybrids between SV40-transformed hamster and mouse cells.SV40转化的仓鼠细胞与小鼠细胞杂交体中的逆转。
Int J Cancer. 1973 Jul 15;12(1):148-61. doi: 10.1002/ijc.2910120116.
9
Positive control of transformed phenotype in hybrids between SV40-transformed and normal human cells.SV40 转化的人类细胞与正常人类细胞杂交中转化表型的阳性控制。
Science. 1974 Jun 21;184(4143):1288-9. doi: 10.1126/science.184.4143.1288.
10
Another chromosomal assignment for a simian virus 40 integration site in human cells.猿猴病毒40在人类细胞中整合位点的另一种染色体定位。
Proc Natl Acad Sci U S A. 1978 Sep;75(9):4460-4. doi: 10.1073/pnas.75.9.4460.
引用本文的文献
1
Chromosome abnormalities in metastatic melanoma.转移性黑色素瘤中的染色体异常
In Vitro Cell Dev Biol Anim. 1994 Feb;30A(2):79-84. doi: 10.1007/BF02631396.
2
Identity of human epidermal growth factor (EGF) receptor with glycoprotein SA-7: evidence for differential phosphorylation of the two components of the EGF receptor from A431 cells.人表皮生长因子（EGF）受体与糖蛋白SA-7的同一性：来自A431细胞的EGF受体两个组分差异磷酸化的证据。
Proc Natl Acad Sci U S A. 1982 Aug;79(16):5026-30. doi: 10.1073/pnas.79.16.5026.
3
Genetic analysis of epidermal growth factor action: assignment of human epidermal growth factor receptor gene to chromosome 7.表皮生长因子作用的遗传分析：人表皮生长因子受体基因定位于7号染色体
Proc Natl Acad Sci U S A. 1980 Jul;77(7):4188-92. doi: 10.1073/pnas.77.7.4188.
4
5
Chromosomal localization of a human band 3-like gene to region 7q35----7q36.人类类带3基因在染色体上定位于7q35至7q36区域。
Am J Hum Genet. 1986 Sep;39(3):307-16.
6
Biochemical and genetic exclusion of calmodulin as the site of the basic defect in cystic fibrosis.钙调蛋白作为囊性纤维化基本缺陷位点的生化与遗传学排除研究
Hum Genet. 1987 Jul;76(3):278-82. doi: 10.1007/BF00283623.
7
Partial trisomy for the long arm of chromosome 7 due to familial balanced translocation.由于家族性平衡易位导致的7号染色体长臂部分三体性。
Hum Genet. 1979 Jul 18;49(3):283-9. doi: 10.1007/BF00569348.
8
Genetic analysis of the human cell surface: antigenic marker for the human X chromosome in human-mouse hybrids.
Proc Natl Acad Sci U S A. 1978 May;75(5):2363-7. doi: 10.1073/pnas.75.5.2363.
9
Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1).定义一种阶段特异性小鼠胚胎抗原（SSEA-1）的单克隆抗体。
Proc Natl Acad Sci U S A. 1978 Nov;75(11):5565-9. doi: 10.1073/pnas.75.11.5565.
本文引用的文献
1
Counting actively metabolizing tissue cultured cells.计数活跃代谢的组织培养细胞。
Exp Cell Res. 1957 Oct;13(2):341-7. doi: 10.1016/0014-4827(57)90013-7.
2
The use of drug-resistant markers to study the hybridization of mouse fibroblasts.使用耐药标记物研究小鼠成纤维细胞的杂交。
Exp Cell Res. 1966 Jan;41(1):190-6. doi: 10.1016/0014-4827(66)90558-1.
3
Surface antigens of mammalian cells as genetic markers. II.哺乳动物细胞的表面抗原作为遗传标记。II.
J Exp Med. 1973 Jul 1;138(1):229-44. doi: 10.1084/jem.138.1.229.
4
Somatic cell hybrids between mouse peritoneal macrophages and SV40-transformed human cells. I. Positive control of the transformed phenotype by the human chromosome 7 carrying the SV40 genome.小鼠腹腔巨噬细胞与SV40转化的人细胞之间的体细胞杂种。I. 携带SV40基因组的人7号染色体对转化表型的阳性控制。
J Exp Med. 1974 Nov 1;140(5):1221-9. doi: 10.1084/jem.140.5.1221.
5
Concordant segregation of the expression of SV40 T antigen and human chromosome 7 in mouse-human hybrid subclones.小鼠 - 人杂交亚克隆中SV40 T抗原表达与人类7号染色体的一致分离。
J Exp Med. 1974 May 1;139(5):1350-3. doi: 10.1084/jem.139.5.1350.
6
Genetic analysis with human--mouse somatic cell hybrids.人类-小鼠体细胞杂种的遗传分析。
Nature. 1969 Jul 26;223(5204):358-63. doi: 10.1038/223358a0.
7
A rapid banding technique for human chromosomes.一种用于人类染色体的快速显带技术。
Lancet. 1971 Oct 30;2(7731):971-2. doi: 10.1016/s0140-6736(71)90287-x.
8
Cell-mediated immunoselection against cell-surface antigens of somatic cell hybrids.
Somatic Cell Genet. 1975 Apr;1(2):123-35. doi: 10.1007/BF01538543.
9
10
Cell-mediated cytotoxicity to SV40-specific tumour-associated antigens.
Nature. 1976 May 27;261(5558):312-4. doi: 10.1038/261312a0.
Zotero 插件