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在对丝状真菌进行阿尼芬净药敏试验中,将纸片扩散法与微量稀释法进行比较的评估。

Evaluation of the disk diffusion method compared to the microdilution method in susceptibility testing of anidulafungin against filamentous fungi.

作者信息

Maida Carmelo Massimo, Milici Maria Eleonora, Trovato Laura, Oliveri Salvatore, Amodio Emanuele, Spreghini Elisabetta, Scalise Giorgio, Barchiesi Francesco

机构信息

Istituto di Malattie Infettive e Medicina Pubblica, Università Politecnica delle Marche, Azienda Ospedaliera-Universitaria, Ospedali Riuniti, Torrette di Ancona, Ancona, Italy.

出版信息

J Clin Microbiol. 2008 Dec;46(12):4071-4. doi: 10.1128/JCM.01088-08. Epub 2008 Oct 15.

DOI:10.1128/JCM.01088-08
PMID:18923014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2593298/
Abstract

Susceptibility testing of anidulafungin (AFG) against 32 mold isolates showed an excellent correlation between disk diffusion (DD) and broth microdilution methods. Based on our data, a 2-microg disk of AFG and a 24-h reading time might represent the best parameters for AFG DD testing against filamentous fungi.

摘要

阿尼芬净(AFG)对32株霉菌分离株的药敏试验表明,纸片扩散法(DD)和肉汤微量稀释法之间具有良好的相关性。根据我们的数据,2μg阿尼芬净纸片和24小时的读数时间可能是针对丝状真菌进行阿尼芬净DD试验的最佳参数。

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