Yang Da-Peng, Cui Da-Xiang
Department of Bio-Nano Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Institute of Micro and Nano Science and Technology, Shanghai Jiao Tong University, Shanghai.
Chem Asian J. 2008 Dec 1;3(12):2010-22. doi: 10.1002/asia.200800195.
With the development of nanotechnology, many novel nanomaterials with unique properties such as magnetic, electronics, and photonics are increasingly being exploited. Gold nanorods, which are rod-shaped nanomaterials, show powerful potential in biological/biomedical fields, especially photothermal therapy, biosensing, imaging, and gene delivery for the treatment of cancer. Many scientific groups have shown strong interests in gold nanorods and have attempted to push them towards possible clinical applications. However, owing to the quantum-size effects of nanomaterials, people have also raised some concerns about the potential toxicity hazards. Therefore, it is becoming urgent to study and exploit the biological effects of gold nanorods for benefit in the near future.
随着纳米技术的发展，许多具有独特性质（如磁性、电子学和光子学性质）的新型纳米材料正越来越多地得到开发利用。金纳米棒作为一种棒状纳米材料，在生物/生物医学领域展现出巨大潜力，尤其是在光热疗法、生物传感、成像以及用于癌症治疗的基因递送方面。许多科研团队对金纳米棒表现出浓厚兴趣，并试图推动其走向可能的临床应用。然而，由于纳米材料的量子尺寸效应，人们也对其潜在的毒性危害提出了一些担忧。因此，在不久的将来，研究和开发金纳米棒的生物学效应以实现其益处变得愈发迫切。
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