Simón F, Muro A, Cordero M, Martin J
Laboratory of Parasitology, Faculty of Pharmacy, University of Salamanca, Spain.
Trop Med Parasitol. 1991 Jun;42(2):106-8.
The objective of this work is to define the prevalence of IgM and IgG antibodies against Dirofilaria immitis in an exposed human population. 395 individuals attending primary care facilities in an area endemic with canine dirofilariasis were studied, as well as 100 non exposed individuals. An ELISA method was used for the detection of IgG and IgM antidirofilarial antibodies. Sera were preadsorbed with antigens of Toxocara canis, Ascaris suum, Echinoccocus granulosus and Fasciola hepatica to prevent cross reactions. Global seroprevalence was 9.3%. IgG antibodies were observed in the oldest sector of the population, while IgM antibodies were found only in its youngest half. No sex differences were observed. This result show that dirofilariasis is common in humans from endemic areas. Repeated contacts with the parasite are common and begin at a young age.
这项工作的目的是确定暴露于伊氏锥虫的人群中抗犬恶丝虫IgM和IgG抗体的流行情况。对395名在犬恶丝虫病流行地区的初级保健机构就诊的个体以及100名未暴露个体进行了研究。采用ELISA方法检测IgG和IgM抗恶丝虫抗体。血清先用犬弓首蛔虫、猪蛔虫、细粒棘球绦虫和肝片吸虫的抗原进行预吸附，以防止交叉反应。总体血清阳性率为9.3%。IgG抗体在年龄最大的人群中被观察到，而IgM抗体仅在年龄最小的一半人群中被发现。未观察到性别差异。这一结果表明，恶丝虫病在流行地区的人群中很常见。反复接触该寄生虫很常见，且始于幼年。
