Meltzer Sara M, Monk Bradley J, Tewari Krishnansu S
Department of Obstetrics and Gynecology, University of California, Irvine, Medical Center, Orange, CA, USA.
Am J Obstet Gynecol. 2009 Mar;200(3):233.e1-7. doi: 10.1016/j.ajog.2008.07.064. Epub 2008 Nov 18.
This review evaluates the antiviral, antioxidant, and immunostimulatory properties of green tea catechins. Two randomized trials evaluating the activity and efficacy of green tea catechins in the management of external genital warts are presented, and the reported side effects associated with this topical treatment modality are outlined. Finally, the mechanism of action, percent of wart clearance, time to clearance, and toxicity profile of green tea catechins are compared with those of podofilox and imiquimod, 2 other patient-administered topical agents approved for treatment of anogenital warts.
本综述评估了绿茶儿茶素的抗病毒、抗氧化和免疫刺激特性。介绍了两项评估绿茶儿茶素治疗尖锐湿疣活性和疗效的随机试验，并概述了与这种局部治疗方式相关的报道副作用。最后，将绿茶儿茶素的作用机制、疣体清除率、清除时间和毒性特征与鬼臼毒素和咪喹莫特这两种其他已获批准用于治疗肛门生殖器疣的患者自行使用的局部用药进行了比较。
