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接触切换作为疫情爆发的控制策略。

Contact switching as a control strategy for epidemic outbreaks.

作者信息

Risau-Gusman Sebastián, Zanette Damián H

机构信息

Consejo Nacional de Investigaciones Científicas y Técnicas, Centro Atómico Bariloche, 8400 San Carlos de Bariloche, Río Negro, Argentina.

出版信息

J Theor Biol. 2009 Mar 7;257(1):52-60. doi: 10.1016/j.jtbi.2008.10.027. Epub 2008 Nov 8.

Abstract

We study the effects of switching social contacts as a strategy to control epidemic outbreaks. Connections between susceptible and infective individuals can be broken by either individual, and then reconnected to a randomly chosen member of the population. It is assumed that the reconnecting individual has no previous information on the epidemiological condition of the new contact. We show that reconnection can completely suppress the disease, both by continuous and discontinuous transitions between the endemic and the infection-free states. For diseases with an asymptomatic phase, we analyze the conditions for the suppression of the disease, and show that-even when these conditions are not met-the increase of the endemic infection level is usually rather small. We conclude that, within some simple epidemiological models, contact switching is a quite robust and effective control strategy. This suggests that it may also be an efficient method in more complex situations.

摘要

我们研究了通过切换社交接触作为控制疫情爆发的一种策略所产生的效果。易感个体与感染个体之间的联系可以由任何一方中断,然后重新连接到人群中随机选择的一个成员。假设重新连接的个体之前不了解新接触者的流行病学状况。我们表明,通过地方病状态和无感染状态之间的连续和不连续转变,重新连接可以完全抑制疾病。对于有无症状阶段的疾病,我们分析了抑制疾病的条件,并表明即使这些条件不满足,地方病感染水平的增加通常也相当小。我们得出结论,在一些简单的流行病学模型中,接触切换是一种相当稳健且有效的控制策略。这表明在更复杂的情况下,它也可能是一种有效的方法。

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