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利用自适应光学光学相干断层扫描技术进行细胞分辨率的活体视网膜容积成像。

Cellular resolution volumetric in vivo retinal imaging with adaptive optics-optical coherence tomography.

作者信息

Zawadzki Robert J, Choi Stacey S, Fuller Alfred R, Evans Julia W, Hamann Bernd, Werner John S

机构信息

Vision Science and Advanced Retinal Imaging Laboratory (VSRI), Department of Ophthalmology & Vision Science,University of California Davis, 4860 Y Street, Suite 2400, Sacramento, California 95817, USA.

出版信息

Opt Express. 2009 Mar 2;17(5):4084-94. doi: 10.1364/oe.17.004084.

DOI:10.1364/oe.17.004084
PMID:19259248
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2715892/
Abstract

Ultrahigh-resolution adaptive optics-optical coherence tomography (UHR-AO-OCT) instrumentation allowing monochromatic and chromatic aberration correction was used for volumetric in vivo retinal imaging of various retinal structures including the macula and optic nerve head (ONH). Novel visualization methods that simplify AO-OCT data viewing are presented, and include co-registration of AO-OCT volumes with fundus photography and stitching of multiple AO-OCT sub-volumes to create a large field of view (FOV) high-resolution volume. Additionally, we explored the utility of Interactive Science Publishing by linking all presented AO-OCT datasets with the OSA ISP software.

摘要

使用允许进行单色和色差校正的超高分辨率自适应光学光学相干断层扫描（UHR-AO-OCT）仪器对包括黄斑和视神经乳头（ONH）在内的各种视网膜结构进行活体视网膜体积成像。提出了简化AO-OCT数据查看的新型可视化方法，包括将AO-OCT体积与眼底摄影进行配准，以及拼接多个AO-OCT子体积以创建大视野（FOV）高分辨率体积。此外，我们通过将所有呈现的AO-OCT数据集与OSA ISP软件链接，探索了交互式科学出版的效用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/2715892/711475c69000/nihms124295f8.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/2715892/e542b12c8a17/nihms124295f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/2715892/f2f403ddf9af/nihms124295f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/2715892/711475c69000/nihms124295f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/2715892/b7a850bbde17/nihms124295f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/2715892/a240f64a59d6/nihms124295f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/2715892/2ea2d5531ff4/nihms124295f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/2715892/8b50251db212/nihms124295f4.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c4/2715892/711475c69000/nihms124295f8.jpg

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