Hansen E S
Institute of Social Medicine, University of Copenhagen, Denmark.
Am J Ind Med. 1991;20(3):401-9. doi: 10.1002/ajim.4700200312.
This study was set up to investigate potential chronic health effects associated with molding in the foundry industry. For this purpose, a cohort of 632 male molders was followed through 10 years with regard to cause-specific mortality. Comparisons were made with another cohort of skilled workers. The mortality from cancer was increased among the molders (standardized mortality ratio 152, 95% confidence interval 100-221), mainly because of an excess number of deaths from bladder cancer (standardized mortality ratio 896, 95% confidence interval 329-1,949). It is suggested that certain mold types may emit bladder carcinogens. In addition, phenols, cresols, and aldehydes in the foundry work atmosphere might act as tumor promoters.
本研究旨在调查铸造行业中与造型相关的潜在慢性健康影响。为此，对一组632名男性造型工人进行了为期10年的特定病因死亡率跟踪调查。与另一组技术工人进行了比较。造型工人的癌症死亡率有所增加（标准化死亡比为152，95%置信区间为100 - 221），主要是因为膀胱癌死亡人数过多（标准化死亡比为896，95%置信区间为329 - 1949）。研究表明，某些造型类型可能会释放膀胱致癌物。此外，铸造工作环境中的酚类、甲酚和醛类可能起到肿瘤促进剂的作用。
