Sandie Reatha, Palidwor Gareth A, Huska Matthew R, Porter Christopher J, Krzyzanowski Paul M, Muro Enrique M, Perez-Iratxeta Carolina, Andrade-Navarro Miguel A
Ottawa Health Research Institute, 501 Smyth Road, Ottawa, ON K1H 8L6, Canada.
BMC Res Notes. 2009 Mar 10;2:39. doi: 10.1186/1756-0500-2-39.
Currently one of the largest online repositories for human and mouse stem cell gene expression data, StemBase was first designed as a simple web-interface to DNA microarray data generated by the Canadian Stem Cell Network to facilitate the discovery of gene functions relevant to stem cell control and differentiation.
Since its creation, StemBase has grown in both size and scope into a system with analysis tools that examine either the whole database at once, or slices of data, based on tissue type, cell type or gene of interest. As of September 1, 2008, StemBase contains gene expression data (microarray and Serial Analysis of Gene Expression) from 210 stem cell samples in 60 different experiments.
StemBase can be used to study gene expression in human and murine stem cells and is available at http://www.stembase.ca.
StemBase是目前最大的人类和小鼠干细胞基因表达数据在线储存库之一,最初设计为一个简单的网络界面,用于展示加拿大干细胞网络生成的DNA微阵列数据,以促进与干细胞控制和分化相关的基因功能的发现。
自创建以来,StemBase在规模和范围上都有所增长,成为一个具有分析工具的系统,这些工具可以一次性检查整个数据库,也可以根据组织类型、细胞类型或感兴趣的基因检查数据切片。截至2008年9月1日,StemBase包含来自60个不同实验中210个干细胞样本的基因表达数据(微阵列和基因表达系列分析)。
StemBase可用于研究人类和小鼠干细胞中的基因表达,可通过http://www.stembase.ca获取。