Lee Jooeun, Lee Chang Hwan, Choi Jaewan, Yoon Sam Young, Sung Kyung Rim, Park Seong Bae, Kook Michael S
Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea.
Korean J Ophthalmol. 2009 Mar;23(1):27-31. doi: 10.3341/kjo.2009.23.1.27. Epub 2009 Mar 9.
To compare the intraocular pressures (IOPs) measured by dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT), and to investigate the association of IOPs on eyes of varying central corneal thickness (CCT).
In this prospective study, 451 eyes of 233 subjects were enrolled. IOPs were measured by GAT and DCT. CCT was measured three times and the average was calculated. Each eye was classified into one of three groups according to CCT: low CCT (group A, CCT<520 microm, n=146); normal CCT (group B, 520 microm<or=CT<or=550 microm, n=163); and high CCT (group C, CCT>550 microm, n=142). In each group, we investigated the association of CCT with IOP measurement by GAT and DCT.
The IOPs measured by GAT and DCT were significantly associated for all eyes (R=0.853, p<0.001, Pearson correlation). CCT was related with both IOP measurement by GAT and DCT with statistical significance (mixed effect model, p<0.001). However, subgroup analysis showed that CCT affected IOP measured by GAT for groups B and C, whereas it affected IOP measured by DCT only for group C.
IOP measured by DCT was not affected by CCT in eyes with low to normal CCT, whereas this measurement was affected in eyes of high CCT range. CCT may have less effect on IOP measurements using DCT than those obtained by GAT, within a specified range of CCT.
比较动态轮廓眼压计（DCT）和Goldmann压平眼压计（GAT）测量的眼内压（IOP），并研究不同中央角膜厚度（CCT）的眼睛中IOP的相关性。
在这项前瞻性研究中，纳入了233名受试者的451只眼睛。通过GAT和DCT测量IOP。测量CCT三次并计算平均值。根据CCT将每只眼睛分为三组之一：低CCT（A组，CCT<520微米，n = 146）；正常CCT（B组，520微米≤CCT≤550微米，n = 163）；高CCT（C组，CCT> 550微米，n = 142）。在每组中，我们研究了CCT与通过GAT和DCT测量的IOP之间的相关性。
所有眼睛通过GAT和DCT测量的IOP均具有显著相关性（R = 0.853，p <0.001，Pearson相关性）。CCT与通过GAT和DCT测量的IOP均具有统计学意义（混合效应模型，p <0.001）。然而，亚组分析表明，CCT影响B组和C组通过GAT测量的IOP，而仅影响C组通过DCT测量的IOP。
在CCT低至正常的眼睛中，通过DCT测量的IOP不受CCT影响，而在高CCT范围内的眼睛中该测量受到影响。在特定的CCT范围内，CCT对使用DCT测量IOP的影响可能小于对使用GAT测量IOP的影响。
