Department of Clinical Sciences, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, P.O. Box 7054, S-750 07 Uppsala, Sweden.
Vet J. 2010 Jun;184(3):264-8. doi: 10.1016/j.tvjl.2009.05.010. Epub 2009 May 31.
Proliferative enteropathy caused by the intracellular bacterium Lawsonia intracellularis is an endemic disease with high herd prevalences reported worldwide. The infection has a considerable impact on pig production and herd economics and, with the development of new diagnostic techniques, L. intracellularis is being identified in an increasing number of pig herds and a wider range of species. This paper reviews current knowledge of the disease, with a focus on the epidemiology in pigs. The prevalence of infection, transmission, predisposing factors, microbial features, pathogenesis, clinical signs, diagnosis, treatment and control are discussed. The disease is mainly controlled by antibiotic treatment and vaccination at herd level. In the development of effective measures to prevent the spread of the infection, increased knowledge of the transmission and persistence of the microorganism are crucial.
由细胞内细菌劳森氏菌引起的增殖性肠病是一种地方性疾病，全球范围内有很高的畜群流行率。该感染对养猪生产和畜群经济有重大影响，随着新诊断技术的发展，越来越多的猪群和更多的物种中都发现了劳森氏菌。本文综述了该病的最新知识，重点介绍了猪的流行病学。讨论了感染的流行率、传播、易患因素、微生物特征、发病机制、临床症状、诊断、治疗和控制。该病主要通过在畜群层面使用抗生素治疗和接种疫苗进行控制。在制定有效的措施来防止感染的传播时，增加对微生物传播和持续存在的认识至关重要。
