Anti-arthritic potential of the plant Justicia gendarussa Burm F.

OBJECTIVE

To evaluate the anti-arthritic potential of the plant Justicia gendarussa using two different rat models.

MATERIALS AND METHOD

The anti-arthritic potential of the alcoholic extract of the plant Justicia gendarussa was evaluated using the Freund's adjuvant-induced and collagen-induced arthritic rat models. The rats were treated with the ethanolic extract of Justicia gendarussa and with standard aspirin.

RESULTS

The ethanolic extract of Justicia gendarussa showed significant anti-arthritic activity that was statistically similar to that of aspirin. Our results suggest that the alcoholic extract of Justicia gendarussa exhibits significant anti-arthritic potential.