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人视网膜的高速光谱域偏振敏感光学相干断层扫描

High speed spectral domain polarization sensitive optical coherence tomography of the human retina.

作者信息

Götzinger Erich, Pircher Michael, Hitzenberger Christoph K

出版信息

Opt Express. 2005 Dec 12;13(25):10217-29. doi: 10.1364/opex.13.010217.

DOI:10.1364/opex.13.010217
PMID:19503236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2978948/
Abstract

We developed a high-speed polarization sensitive optical coherence tomography (PS-OCT) system for retinal imaging based on spectral domain OCT. The system uses two spectrometers, one for each polarization channel, that operate in parallel at 20000 A-lines/s each. It provides reflectivity, retardation, and cumulative optic axis orientation simultaneously. We present our instrument and discuss the requirements for the alignment of the two spectrometers specific for our setup. We show 2D spectral domain PS-OCT images and - to the best of our knowledge - the first 3D spectral domain PS-OCT data sets in form of fly-through movies and volume rendered data sets recorded in human retina in vivo.

摘要

我们基于谱域光学相干断层扫描(OCT)技术开发了一种用于视网膜成像的高速偏振敏感光学相干断层扫描(PS-OCT)系统。该系统使用两台光谱仪,每个偏振通道各一台,每台以每秒20000条A线的速度并行运行。它能同时提供反射率、相位延迟和累积光轴方向信息。我们展示了我们的仪器,并讨论了针对我们的设置对两台光谱仪进行对准的要求。我们展示了二维谱域PS-OCT图像,并且据我们所知,还展示了以飞行浏览电影形式呈现的首个三维谱域PS-OCT数据集以及在人体视网膜活体中记录的体绘制数据集。

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