Bell D S, Clements R S, Perentesis G, Roddam R, Wagenknecht L
Division of Endocrinology and Metabolism, University of Alabama, Birmingham.
Arch Intern Med. 1991 Nov;151(11):2265-9.
The accuracy of patients and health care professionals in drawing up the components of a split-mix insulin regimen and of premixed insulin at three dosages (30 units, 10 units, and 5 units) was assessed with both 30-U and 100-U syringes. Both patients and professionals were inaccurate with both syringes. At low doses tested and with both syringes, patients and professionals showed greater accuracy with premixed insulin than with self-mixed insulin. Errors in drawing up insulin involved errors mainly in the ratio rather than the total volume of insulin drawn. Accuracy improved with higher doses of insulin. The patients' perception of their skill level in drawing up and mixing insulin correlated with the objective measurements of their skill. The improved accuracy in dosing with premixed insulin might explain the previously observed improved glycemic control in patients taking premixed insulin.
使用30单位和100单位的注射器，评估了患者和医护人员在调配三种剂量（30单位、10单位和5单位）的预混胰岛素和混合胰岛素方案成分时的准确性。患者和医护人员使用两种注射器时均不准确。在测试的低剂量下，使用两种注射器时，患者和医护人员调配预混胰岛素的准确性高于自行混合胰岛素。抽取胰岛素时的误差主要涉及胰岛素比例而非抽取的总体积。胰岛素剂量越高，准确性越高。患者对自己抽取和混合胰岛素技能水平的认知与他们技能的客观测量结果相关。预混胰岛素给药准确性的提高可能解释了之前观察到的使用预混胰岛素患者血糖控制改善的现象。
