Grzyska Ulrich, Fiehler Jens
Department of Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Klin Neuroradiol. 2009 Mar;19(1):82-90. doi: 10.1007/s00062-009-8035-y. Epub 2009 May 15.
Cerebral arteriovenous malformations (AVMs) are a major source of intracerebral hemorrhage in younger adults. First, some basic ideas about AVM anatomy, the influences of pressure, macrovascular flow, perfusion and the "steal effect", and some recent observations in the field of inflammatory markers and genetics are briefly discussed. Then, some clinical aspects in the presentation and the natural course of AVMs are highlighted, with special emphasis on the prediction of hemorrhage. Finally, some problems of the current treatment options are mentioned, and future directions in diagnostics and therapy considered.
脑动静脉畸形（AVM）是年轻成年人脑出血的主要来源。首先，简要讨论一些关于AVM解剖结构、压力、大血管血流、灌注及“盗血效应”的基本概念，以及该领域在炎症标志物和遗传学方面的一些最新观察结果。然后，重点强调AVM临床表现和自然病程中的一些临床方面，特别关注出血的预测。最后，提及当前治疗方案存在的一些问题，并探讨诊断和治疗的未来方向。
