Pang Yi, Trachimowicz Ruth, Castells David D, Goodfellow Geoffrey W, Maino Dominick M
Illinois College of Optometry, Chicago, Illinois 60616, USA.
Optom Vis Sci. 2009 Dec;86(12):1346-51. doi: 10.1097/OPX.0b013e3181be0712.
To characterize optic nerve head (ONH) parameters including symmetry between the eyes in healthy African American children using the Heidelberg retinal tomograph II, and to determine if there are associations between these parameters and age, refractive error, or gender.
The ONHs of 146 African American children aged 6 to 17 years without ocular disease were imaged with the Heidelberg retinal tomograph II. Mean values for 11 ONH parameters were determined as was their relationship to age, gender, and refractive error. Interocular symmetry of the parameters was determined.
The mean (+/-standard deviation) disc area, rim area, and cup area were 2.18 +/- 0.57 mm2, 1.63 +/- 0.40 mm2, and 0.52 +/- 0.37 mm2, respectively. The mean linear cup-to-disc (C/D) ratio was 0.45 +/- 0.15, and mean cup depth was 0.22 +/- 0.10 mm. The mean retinal nerve fiber layer thickness was 0.26 +/- 0.07 mm. The ONH parameters were not related to age or refractive error. With the exception of the C/D area ratio and linear C/D ratio, which were greater in boys than in girls, ONH parameters were not related to gender. Most parameters were strongly correlated between the right and left eyes. The average interocular differences in disc area, cup area, rim area, linear C/D ratio, and mean retinal nerve fiber layer thickness were 0.09 +/- 0.31 mm2, 0.04 +/- 0.22 mm2, 0.06 +/- 0.40 mm2, 0.02 +/- 0.11, and 0.00 +/- 0.06 mm2, respectively.
ONH parameters were not related to age and refractive error, and only C/D area ratio and linear C/D ratio were greater in boys than girls in a clinical sample of African American children. These measures of normative ONH parameters and range of interocular differences may be helpful in clinical pediatric eye care to facilitate identification of African American children with abnormal optic discs.
使用海德堡视网膜断层扫描仪II对健康非裔美国儿童的视神经乳头（ONH）参数进行特征描述，包括双眼之间的对称性，并确定这些参数与年龄、屈光不正或性别之间是否存在关联。
使用海德堡视网膜断层扫描仪II对146名年龄在6至17岁、无眼部疾病的非裔美国儿童的ONH进行成像。确定了11个ONH参数的平均值及其与年龄、性别和屈光不正的关系。确定了参数的双眼对称性。
平均（±标准差）视盘面积、视盘边缘面积和视杯面积分别为2.18±0.57mm²、1.63±0.40mm²和0.52±0.37mm²。平均线性杯盘（C/D）比为0.45±0.15，平均视杯深度为0.22±0.10mm。平均视网膜神经纤维层厚度为0.26±0.07mm。ONH参数与年龄或屈光不正无关。除了男孩的C/D面积比和线性C/D比大于女孩外，ONH参数与性别无关。大多数参数在右眼和左眼之间高度相关。视盘面积、视杯面积、视盘边缘面积、线性C/D比和平均视网膜神经纤维层厚度的平均双眼差异分别为0.09±0.31mm²、0.04±0.22mm²、0.06±0.40mm²、0.02±0.11和0.00±0.06mm²。
在非裔美国儿童的临床样本中，ONH参数与年龄和屈光不正无关，只有C/D面积比和线性C/D比男孩大于女孩。这些正常ONH参数的测量值和双眼差异范围可能有助于临床儿科眼科护理，以促进识别视盘异常的非裔美国儿童。
