Asonuma K, Takaya S, Selby R, Okamoto R, Yamamoto Y, Yokoyama T, Todo S, Ozawa K, Starzl T E
Second Department of Surgery, Faculty of Medicine, Kyoto University, Japan.
Transplantation. 1991 Jan;51(1):164-71. doi: 10.1097/00007890-199101000-00025.
Arterial ketone body ratio (AKBR) was measured sequentially in 84 liver transplantations (OLTx). These transplantation procedures were classified into 3 groups with respect to graft survival and patient condition at the end of the first month (Group A, the grafts survived longer than 1 month with satisfactory patient condition; Group B, the grafts survived longer than 1 month but the patients were ICU-bound; Group C, the grafts were lost and the patients died or underwent re-OLTx). In Group A, the AKBR was elevated to above 1.0 by the second postoperative day. In Group B, the AKBR was elevated to above 0.7 but stayed below 1.0 during this period. In Group C, the AKBR remained below 0.7 longer than 2 days after operation. Although conventional liver function tests showed significant increases in Groups B and C as compared with Group A, they were less specific in predicting ultimate graft survival.
对84例肝移植（原位肝移植）患者依次测量动脉酮体比率（AKBR）。这些移植手术根据术后第一个月末的移植物存活情况和患者状况分为3组（A组，移植物存活超过1个月且患者状况良好；B组，移植物存活超过1个月但患者需入住重症监护病房；C组，移植物失活且患者死亡或接受再次原位肝移植）。在A组中，术后第二天AKBR升高至1.0以上。在B组中，AKBR升高至0.7以上，但在此期间一直低于1.0。在C组中，术后2天以上AKBR仍低于0.7。尽管与A组相比，B组和C组的传统肝功能检查结果有显著升高，但它们在预测最终移植物存活方面的特异性较低。
