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吞噬性白细胞慢性病毒血症继发的巨细胞病毒性视网膜炎。

Cytomegalovirus retinitis secondary to chronic viremia in phagocytic leukocytes.

作者信息

Fiala M, Chatterjee S N, Carson S, Poolsawat S, Heiner D C, Saxon A, Guze L B

出版信息

Am J Ophthalmol. 1977 Oct;84(4):567-73. doi: 10.1016/0002-9394(77)90454-8.

DOI:10.1016/0002-9394(77)90454-8
PMID:199065
Abstract

We studied the relationship between the duration and intensity of cytomegalovirus viremia, cytomegalovirus complement fixing antibody, and cytomegalovirus retinitis in 61 renal transplant recipients. Five (8%) patients had chronic viremia which lasted more than six months. Two of the five developed typical cytomegalovirus retinitis and a severe fungal infection after intensive viremia of more than 11 months' duration. Retinitis did not develop in 22 patients with short-term viremia. Infectious cytomegalovirus was largely associated with polymorphonuclear leukocytes, but the virus was associated with monocytes during the immature granulocytic response accompanying one patient's terminal illness.

摘要

我们研究了61例肾移植受者中巨细胞病毒血症的持续时间和强度、巨细胞病毒补体结合抗体与巨细胞病毒性视网膜炎之间的关系。5例(8%)患者出现持续超过6个月的慢性病毒血症。这5例患者中有2例在持续超过11个月的强烈病毒血症后发生了典型的巨细胞病毒性视网膜炎和严重的真菌感染。22例短期病毒血症患者未发生视网膜炎。感染性巨细胞病毒在很大程度上与多形核白细胞相关,但在1例患者终末期疾病伴随的未成熟粒细胞反应期间,该病毒与单核细胞相关。

相似文献

1
Cytomegalovirus retinitis secondary to chronic viremia in phagocytic leukocytes.吞噬性白细胞慢性病毒血症继发的巨细胞病毒性视网膜炎。
Am J Ophthalmol. 1977 Oct;84(4):567-73. doi: 10.1016/0002-9394(77)90454-8.
2
Epidemiology of cytomegalovirus infection after transplantation and immunosuppression.移植及免疫抑制后巨细胞病毒感染的流行病学
J Infect Dis. 1975 Oct;132(4):421-33. doi: 10.1093/infdis/132.4.421.
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Primary cytomegalovirus and opportunistic infections. Incidence in renal transplant recipients.原发性巨细胞病毒感染与机会性感染。肾移植受者中的发病率。
JAMA. 1978 Nov 24;240(22):2446-9.
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Risk for retinitis in patients with AIDS can be assessed by quantitation of threshold levels of cytomegalovirus DNA burden in blood.艾滋病患者发生视网膜炎的风险可通过对血液中巨细胞病毒DNA载量阈值水平进行定量分析来评估。
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Psychiatric disease and cytomegalovirus viremia in renal transplant recipients.肾移植受者的精神疾病与巨细胞病毒血症
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"Triple infections" (fungal, bacterial and viral) in immunosuppressed renal transplant recipients.免疫抑制的肾移植受者中的“三重感染”(真菌、细菌和病毒感染)
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[Serologic diagnosis of primary cytomegalovirus infections in patients following kidney transplantation using the indirect immunofluorescence technic and the complement-fixation test].[运用间接免疫荧光技术和补体结合试验对肾移植患者原发性巨细胞病毒感染进行血清学诊断]
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Cytomegalovirus retinitis in adults. A manifestation of disseminated viral infection.成人巨细胞病毒性视网膜炎。播散性病毒感染的一种表现。
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Cytomegalovirus infection after renal transplantation. Report of a case with viremia and atypical lymphocytosis.肾移植后巨细胞病毒感染。1例病毒血症和非典型淋巴细胞增多症的报告。
JAMA. 1969 Mar 3;207(9):1712-4. doi: 10.1001/jama.207.9.1712.

引用本文的文献

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Cytomegalovirus retinitis and the acquired immunodeficiency syndrome--bench to bedside: LXVII Edward Jackson Memorial Lecture.巨细胞病毒视网膜炎与获得性免疫缺陷综合征——从基础到临床:第十六十七届爱德华·杰克逊纪念讲座。
Am J Ophthalmol. 2011 Feb;151(2):198-216.e1. doi: 10.1016/j.ajo.2010.10.018. Epub 2010 Dec 18.
2
Branch retinal artery occlusion (BRAO) combined with branch retinal vein occlusion (BRVO) and optic disc neovascularization associated with HIV and CMV retinitis.视网膜分支动脉阻塞(BRAO)合并视网膜分支静脉阻塞(BRVO)以及与HIV和巨细胞病毒性视网膜炎相关的视盘新生血管形成。
Int Ophthalmol. 1995;19(4):249-52. doi: 10.1007/BF00132694.
3
Biphasic viremia and viral gene expression in leukocytes during acute cytomegalovirus infection of mice.
小鼠急性巨细胞病毒感染期间白细胞中的双相病毒血症和病毒基因表达
J Virol. 1994 Oct;68(10):6305-11. doi: 10.1128/JVI.68.10.6305-6311.1994.
4
Ophthalmological complications of haemodialysis and kidney transplantation.血液透析和肾移植的眼科并发症
Doc Ophthalmol. 1980 May 30;49(1):v-vii, 1-96. doi: 10.1007/BF00175176.
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Cytomegalovirus retinitis: a manifestation of the acquired immune deficiency syndrome (AIDS).巨细胞病毒性视网膜炎:获得性免疫缺陷综合征(艾滋病)的一种表现。
Br J Ophthalmol. 1983 Jun;67(6):372-80. doi: 10.1136/bjo.67.6.372.
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Disseminated cytomegalovirus infection. Molecular analysis of virus and leukocyte interactions in viremia.播散性巨细胞病毒感染。病毒血症中病毒与白细胞相互作用的分子分析。
J Clin Invest. 1988 Jan;81(1):75-81. doi: 10.1172/JCI113313.
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Role of primary and secondary maternal viremia in transplacental guinea pig cytomegalovirus transfer.母源原发性和继发性病毒血症在豚鼠巨细胞病毒经胎盘传播中的作用。
J Virol. 1990 May;64(5):1991-7. doi: 10.1128/JVI.64.5.1991-1997.1990.
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High levels of circulating cytomegalovirus DNA reflect visceral organ disease in viremic immunosuppressed patients other than marrow recipients.高循环水平的巨细胞病毒DNA反映了除骨髓移植受者外的病毒血症免疫抑制患者的内脏器官疾病。
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Comparison of rates of virus isolation from leukocyte populations separated from blood by conventional and Ficoll-Paque/Macrodex methods.通过传统方法和Ficoll-泛影葡胺/聚明胶肽方法从血液中分离出的白细胞群体的病毒分离率比较。
J Clin Microbiol. 1979 Oct;10(4):533-7. doi: 10.1128/jcm.10.4.533-537.1979.