O-乙酰肟作为可转化的导向基团用于 Pd 催化的 C-H 键功能化反应。
O-acetyl oximes as transformable directing groups for Pd-catalyzed C-H bond functionalization.
机构信息
Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109-1055, USA.
出版信息
Org Lett. 2010 Feb 5;12(3):532-5. doi: 10.1021/ol902720d.
Abstract
O-Acetyl oximes serve as effective directing groups for Pd-catalyzed sp(2) and sp(3) C-H functionalization reactions. The C-H functionalization products can be subsequently transformed into ortho- or beta-functionalized ketones, alcohols, amines, and heterocycles.
摘要
O-乙酰肟基是 Pd 催化的 sp(2)和 sp(3) C-H 功能化反应的有效导向基团。随后，C-H 功能化产物可以转化为邻位或β位官能化的酮、醇、胺和杂环化合物。
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