Monno Rosa, Fumarola Luciana, Trerotoli Paolo, Cavone Domenica, Giannelli Giorgia, Rizzo Caterina, Ciceroni Lorenzo, Musti Marina
Department of Internal Medicine and Public Health, Hygiene Section, School of Medicine, University of Bari, Italy, Piazza G. Cesare 11, 70124 Bari, Italy.
Ann Agric Environ Med. 2009;16(2):205-9.
To establish the seroprevalence of antibodies to C. burnetii, Leptospira and Brucella in subjects at risk of exposure, 128 workers exposed to farm animals and 280 healthy blood donors were studied. Antibodies to C. burnetii, Leptospira and Brucella were determined by indirect immunofluorescence assay, by microagglutination test (MAT) and by standard tube agglutination test, respectively. Of subjects exposed to farm animals 73.4 % were positive for anti C. burnetii IgG (titer > or = 20) compared to 13.6 % of control subjects (p < 0.0001). The seroprevalence was found mainly among the veterinarians (100 %) and the animal breeding workers (84 %). The trend of percentage of positivity to antibodies to C. burnetii is significant only in the group of workers > or = 70 years, when adjusted for sex and occupation. None of the subjects examined had antibodies to Leptospira and Brucella. Further improvements in the occupational hygiene of the work environment is advisable.
为确定有暴露风险人群中抗伯氏考克斯体、钩端螺旋体和布鲁氏菌抗体的血清流行率，对128名接触农场动物的工人和280名健康献血者进行了研究。分别通过间接免疫荧光试验、显微凝集试验（MAT）和标准试管凝集试验测定抗伯氏考克斯体、钩端螺旋体和布鲁氏菌的抗体。接触农场动物的人群中，73.4%的抗伯氏考克斯体IgG呈阳性（滴度≥20），而对照人群中这一比例为13.6%（p<0.0001）。血清流行率主要见于兽医（100%）和动物饲养工人（84%）。在根据性别和职业进行调整后，仅在年龄≥70岁的工人群体中，抗伯氏考克斯体抗体阳性百分比的趋势具有显著性。所有受检对象均未检测到抗钩端螺旋体和布鲁氏菌的抗体。建议进一步改善工作环境的职业卫生状况。
