Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Environ Health Perspect. 2009 Nov;117(11):1713-7. doi: 10.1289/ehp.0900933. Epub 2009 Jul 20.
Several studies show an association between exposure to aircraft or road traffic noise and cardiovascular effects, which may be mediated by a noise-induced release of stress hormones.
Our objective was to assess saliva cortisol concentration in relation to exposure to aircraft noise.
A multicenter cross-sectional study, HYENA (Hypertension and Exposure to Noise near Airports), comprising 4,861 persons was carried out in six European countries. In a subgroup of 439 study participants, selected to enhance the contrast in exposure to aircraft noise, saliva cortisol was assessed three times (morning, lunch, and evening) during 1 day.
We observed an elevation of 6.07 nmol/L [95% confidence interval (CI), 2.32-9.81 nmol/L] in morning saliva cortisol level in women exposed to aircraft noise at an average 24-hr sound level (L(Aeq,24h)) > 60 dB, compared with women exposed to L(Aeq,24h) < or = 50 dB, corresponding to an increase of 34%. Employment status appeared to modify the response. We found no association between noise exposure and saliva cortisol levels in men.
Our results suggest that exposure to aircraft noise increases morning saliva cortisol levels in women, which could be of relevance for noise-related cardiovascular effects.
多项研究表明，暴露于飞机或道路交通噪声与心血管效应之间存在关联，这种关联可能是由噪声引起的应激激素释放所介导的。
我们旨在评估唾液皮质醇浓度与飞机噪声暴露之间的关系。
一项多中心横断面研究，即 HYENA（机场周围的高血压和噪声暴露）研究，在六个欧洲国家进行，共纳入 4861 人。在 439 名研究参与者的亚组中，选择了暴露于飞机噪声的差异较大的参与者，在一天内三次（早晨、午餐和晚上）评估唾液皮质醇。
与暴露于 L(Aeq,24h)≤50 dB 的女性相比，暴露于 L(Aeq,24h)＞60 dB 的女性早晨唾液皮质醇水平升高了 6.07 nmol/L（95%置信区间：2.32-9.81 nmol/L），这相当于增加了 34%。职业状态似乎改变了这种反应。我们未发现噪声暴露与男性唾液皮质醇水平之间存在关联。
我们的研究结果表明，飞机噪声暴露会增加女性早晨唾液皮质醇水平，这可能与噪声相关的心血管效应有关。
Zotero 插件