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Photochemistry of visual pigment in a G(q) protein-coupled receptor (GPCR)--insights from structural and spectral tuning studies on squid rhodopsin.G(q)蛋白偶联受体(GPCR)中视觉色素的光化学——来自鱿鱼视紫红质结构和光谱调谐研究的见解
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Squid rhodopsin and retinochrome.鱿鱼视紫红质和视网膜色素。
Nat New Biol. 1973 May 9;243(123):53-4.
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J Mol Biol. 2001 Nov 30;314(3):455-63. doi: 10.1006/jmbi.2001.5167.
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The counterion-retinylidene Schiff base interaction of an invertebrate rhodopsin rearranges upon light activation.无脊椎动物视紫红质的抗衡离子-视黄醛亚胺席夫碱相互作用在光激活时会发生重排。
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Adaptive Landscapes in the Age of Synthetic Biology.合成生物学时代的适应性景观。
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Analysis of Conserved Glutamate and Aspartate Residues in Drosophila Rhodopsin 1 and Their Influence on Spectral Tuning.果蝇视紫红质1中保守谷氨酸和天冬氨酸残基的分析及其对光谱调谐的影响
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Quantum mechanical/molecular mechanical structure, enantioselectivity, and spectroscopy of hydroxyretinals and insights into the evolution of color vision in small white butterflies.量子力学/分子力学结构、羟基视黄醛的对映选择性和光谱学,以及对小白蛱蝶色觉进化的深入了解。
J Phys Chem B. 2011 Dec 29;115(51):15380-8. doi: 10.1021/jp208107r. Epub 2011 Dec 6.
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Why 11-cis-retinal? Why not 7-cis-, 9-cis-, or 13-cis-retinal in the eye?为什么是 11-顺式-视黄醛?为什么不是 7-顺式-、9-顺式-或 13-顺式-视黄醛在眼睛中?
J Am Chem Soc. 2011 Nov 30;133(47):19052-5. doi: 10.1021/ja208789h. Epub 2011 Nov 3.

本文引用的文献

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Nonempirical Calculation of Polymethine Excited States.
Angew Chem Int Ed Engl. 2001 Sep 3;40(17):3189-3190. doi: 10.1002/1521-3773(20010903)40:17<3189::AID-ANIE3189>3.0.CO;2-E.
2
Conserved waters mediate structural and functional activation of family A (rhodopsin-like) G protein-coupled receptors.保守水域介导A类(视紫红质样)G蛋白偶联受体的结构和功能激活。
Proc Natl Acad Sci U S A. 2009 May 26;106(21):8555-60. doi: 10.1073/pnas.0903545106. Epub 2009 May 11.
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Observation of "ionic lock" formation in molecular dynamics simulations of wild-type beta 1 and beta 2 adrenergic receptors.野生型β1和β2肾上腺素能受体分子动力学模拟中“离子锁”形成的观察
Biochemistry. 2009 Jun 9;48(22):4789-97. doi: 10.1021/bi900299f.
4
Mechanism of spectral tuning going from retinal in vacuo to bovine rhodopsin and its mutants: multireference ab initio quantum mechanics/molecular mechanics studies.从真空环境中的视网膜到牛视紫红质及其突变体的光谱调谐机制:多参考从头算量子力学/分子力学研究
J Phys Chem B. 2008 Dec 25;112(51):16883-90. doi: 10.1021/jp807172h.
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Water-mediated spectral shifts in rhodopsin and bathorhodopsin.视紫红质和视紫红质中间体中的水介导光谱位移。
Photochem Photobiol. 2009 Mar-Apr;85(2):517-20. doi: 10.1111/j.1751-1097.2008.00499.x. Epub 2009 Jan 6.
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Glutamic acid 181 is uncharged in dark-adapted visual rhodopsin.在暗适应的视紫红质中,谷氨酸181呈电中性。
J Am Chem Soc. 2008 Dec 24;130(51):17220-1. doi: 10.1021/ja805992d.
7
Crystallographic structure of xanthorhodopsin, the light-driven proton pump with a dual chromophore.嗜盐菌视紫红质的晶体结构,一种具有双发色团的光驱动质子泵。
Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16561-5. doi: 10.1073/pnas.0807162105. Epub 2008 Oct 15.
8
Crystal structure of squid rhodopsin.鱿鱼视紫红质的晶体结构。
Nature. 2008 May 15;453(7193):363-7. doi: 10.1038/nature06925.
9
Signal transduction: the rhodopsin story continued.信号转导:视紫红质的故事仍在继续。
Nature. 2008 May 15;453(7193):292-3. doi: 10.1038/453292a.
10
Spectral tuning in visual pigments: an ONIOM(QM:MM) study on bovine rhodopsin and its mutants.视觉色素中的光谱调谐:对牛视紫红质及其突变体的ONIOM(量子力学:分子力学)研究
J Phys Chem B. 2008 Jun 5;112(22):6814-27. doi: 10.1021/jp709730b. Epub 2008 May 13.

Photochemistry of visual pigment in a G(q) protein-coupled receptor (GPCR)--insights from structural and spectral tuning studies on squid rhodopsin.

作者信息

Sekharan Sivakumar, Altun Ahmet, Morokuma Keiji

机构信息

Department of Chemistry, Cherry L. Emerson Center for Scientific Computation, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, USA.

出版信息

Chemistry. 2010 Feb 8;16(6):1744-9. doi: 10.1002/chem.200903194.

DOI:10.1002/chem.200903194
PMID:20066712
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2827932/
Abstract
摘要