工程化合成途径的静态和动态控制。
Engineering static and dynamic control of synthetic pathways.
机构信息
Department of Electrical Engineering and Computer Science, University of California at Berkeley, Berkeley, CA 94720, USA.
出版信息
Cell. 2010 Jan 8;140(1):19-23. doi: 10.1016/j.cell.2009.12.029.
PMID:20085699
Abstract
Maximizing the production of a desired small molecule is one of the primary goals in metabolic engineering. Recent advances in the nascent field of synthetic biology have increased the predictability of small-molecule production in engineered cells growing under constant conditions. The next frontier is to create synthetic pathways that adapt to changing environments.
摘要
在代谢工程中，最大限度地生产所需的小分子是主要目标之一。新兴的合成生物学领域的最新进展提高了在恒定条件下生长的工程细胞中小分子生产的可预测性。下一个前沿是创建能够适应不断变化的环境的合成途径。
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