Bak A A, Grobbee D E
Department of Epidemiology and Biostatistics, Erasmus University Rotterdam, The Netherlands.
Am J Clin Nutr. 1991 Apr;53(4):971-5. doi: 10.1093/ajcn/53.4.971.
To study the effects of caffeine on serum lipids and blood pressure, we conducted a double-blind, randomized trial with two parallel groups in 69 young, healthy subjects. After a 3-wk run-in period, subjects were randomly assigned to one of two groups receiving either 4-6 140-mL cups filtered decaffeinated coffee per day and an equal number of pills containing 75 mg caffeine or 4-6 140-mL cups filtered decaffeinated coffee per day and an equal number of placebo pills, for 9 wk. In both groups caffeine intake from other sources was not allowed. The main finding of this study is that abstinence from caffeine for a period of 9 wk has no effect on either serum lipids or blood pressure.
为研究咖啡因对血脂和血压的影响，我们在69名年轻健康受试者中进行了一项双盲、随机、两组平行试验。在为期3周的导入期后，受试者被随机分为两组，一组每天饮用4 - 6杯140毫升过滤脱咖啡因咖啡，并服用等量含75毫克咖啡因的药丸；另一组每天饮用4 - 6杯140毫升过滤脱咖啡因咖啡，并服用等量的安慰剂药丸，为期9周。两组均不允许从其他来源摄入咖啡因。本研究的主要发现是，9周不摄入咖啡因对血脂和血压均无影响。
