预测饮食限制是否会增加迄今尚未测试过的物种的寿命。

Predicting whether dietary restriction would increase longevity in species not tested so far.

机构信息

Université Paul-Sabatier, Centre de Recherche sur la Cognition Animale, UMR CNRS 5169, 118 Route de Narbonne, 31062 Toulouse Cedex 9, France.

出版信息

Ageing Res Rev. 2010 Jul;9(3):289-97. doi: 10.1016/j.arr.2010.01.001. Epub 2010 Jan 25.

DOI:10.1016/j.arr.2010.01.001

PMID:20105461

Abstract

Dietary restriction (DR) is often considered as a nearly universal means to extend longevity in animal species. This article argues that whether DR will increase longevity is dependent on life-history strategies. Long-lived species are not expected to live much longer under DR, contrarily to short-lived ones. However, species able to cover long distances are not expected to live longer under DR, even if they are short-lived. Human beings are long-lived and can also cover long distances: thus, DR would probably not increase their lifespan. One may wonder whether DR mimetics would have some effects in human beings if DR does not increase longevity in this species.

摘要

饮食限制（DR）通常被认为是延长动物物种寿命的一种几乎普遍的手段。本文认为，DR 是否能延长寿命取决于生活史策略。长寿命物种在 DR 下预计不会延长太多寿命，与短寿命物种相反。然而，能够长途跋涉的物种在 DR 下预计也不会延长寿命，即使它们是短寿命的。人类是长寿的，也可以长途跋涉：因此，DR 可能不会延长他们的寿命。人们可能会想，如果 DR 不能延长人类的寿命，那么 DR 模拟物是否会对人类有一些影响。