Biomedicinal Information Research Center, Japan Biological Informatics Consortium, 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan.
J Nat Prod. 2010 Feb 26;73(2):226-8. doi: 10.1021/np900810r.
Two new modified indole-containing peptides, JBIR-34 (1) and JBIR-35 (2), were isolated from the fermentation broth of a sponge-derived actinomycete identified by phylogenetic methods as a Streptomyces sp. (strain Sp080513GE-23). The planar structures of 1 and 2 were assigned on the basis of 1D and 2D NMR spectroscopy and MS analyses. Further, the absolute configurations of the amino acid residues were determined using Marfey's method.
从一种海绵来源的放线菌发酵液中分离到两种新的含吲哚修饰的肽，JBIR-34（1）和 JBIR-35（2）。该放线菌通过系统发育方法鉴定为链霉菌属（菌株 Sp080513GE-23）。根据 1D 和 2D NMR 光谱和 MS 分析确定了 1 和 2 的平面结构。此外，使用 Marfey 法确定了氨基酸残基的绝对构型。
