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在干扰素-α和利巴韦林治疗慢性丙型肝炎病毒感染期间发生的葡萄膜炎-小柳-原田病

Vogt-Koyanagi-Harada disease occurring during interferon-alpha and ribavirin therapy for chronic hepatitis C virus infection.

作者信息

Al-Muammar Abdulrahman M, Al-Mudhaiyan Tariq M, Al Otaibi Mohammed, Abdo Ayman, Abu El-Asrar Ahmed M

机构信息

Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

Int Ophthalmol. 2010 Oct;30(5):611-3. doi: 10.1007/s10792-010-9357-0. Epub 2010 Feb 23.

DOI:10.1007/s10792-010-9357-0
PMID:20177954
Abstract

We report a case of Vogt-Koyanagi-Harada (VKH) disease in a 30-year-old patient who was receiving interferon-alpha and ribavirin therapy for chronic hepatitis C virus infection. The intraocular inflammation responded to systemic corticosteroid and mycophenolate mofetil treatment. Physicians should be aware of the association between interferon-alpha and ribavirin therapy for hepatitis C virus infection and the development of VKH disease.

摘要

我们报告了一例30岁的Vogt-小柳-原田（VKH）病患者，该患者因慢性丙型肝炎病毒感染正在接受α干扰素和利巴韦林治疗。眼部炎症对全身使用皮质类固醇和霉酚酸酯治疗有反应。医生应注意α干扰素和利巴韦林治疗丙型肝炎病毒感染与VKH病发生之间的关联。

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本文引用的文献

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Intraocular complications of IFN-alpha and ribavirin therapy in patients with chronic viral hepatitis C.慢性丙型病毒性肝炎患者接受干扰素-α和利巴韦林治疗的眼内并发症
World J Gastroenterol. 2007 Jun 14;13(22):3137-40. doi: 10.3748/wjg.v13.i22.3137.
2
Interferon-alpha2a and Vogt-Koyanagi-Harada disease: a double-edged sword?干扰素α2a与葡萄膜大脑炎：一把双刃剑？
Int Ophthalmol. 2007 Apr-Jun;27(2-3):211-5. doi: 10.1007/s10792-007-9040-2. Epub 2007 Feb 23.
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Vogt-Koyanagi-Harada disease in patients with chronic hepatitis C.慢性丙型肝炎患者的Vogt-小柳-原田病
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Sofosbuvir/Ribavirin therapy for patients experiencing failure of ombitasvir/paritaprevir/ritonavir + ribavirin therapy: Two cases report and review of literature.索磷布韦/利巴韦林治疗ombitasvir/paritaprevir/ritonavir+利巴韦林治疗失败的患者：两例报告及文献复习
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Vogt-Koyanagi-Harada disease associated with interferon-A and ribavirin therapy for chronic hepatitis C infection.与干扰素-α和利巴韦林治疗慢性丙型肝炎感染相关的葡萄膜炎-小柳-原田病
J Infect. 2006 Feb;52(2):e59-61. doi: 10.1016/j.jinf.2005.05.005. Epub 2005 Jun 13.
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Autoimmune manifestations during interferon therapy in patients with chronic hepatitis C: the hepatologist's view.丙型肝炎患者干扰素治疗期间的自身免疫表现：肝病专家的观点。
Minerva Gastroenterol Dietol. 2005 Mar;51(1):55-61.
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Vogt-Koyanagi-Harada syndrome.伏格特-小柳-原田综合征
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