Nomura A M, Kolonel L N, Hankin J H, Yoshizawa C N
Epidemiology Program, University of Hawaii, Honolulu 96813.
Int J Cancer. 1991 May 10;48(2):199-205. doi: 10.1002/ijc.2910480208.
This dietary study was based on 195 male and 66 female cases of lower urinary tract cancer, identified in Hawaii between 1977 and 1986. Each case was matched for sex, age, and ethnic group (Caucasian or Japanese) to 2 population-based controls. There was a decrease in risk with increasing levels of consumption of vitamin C in women (p = 0.03) and dark green vegetables in men (p = 0.02). When examined by quartile, the odds ratios for the highest quartile of intake compared to the lowest quartile were 0.4 for women and 0.6 for men, respectively. Although dark green vegetables are a source of carotenoids, the intake of total carotenoids, retinol and total vitamin A was weakly and inconsistently related to risk in both sexes. Among women only, there was also an inverse association with the consumption of regular ground coffee (p = 0.02) but not with other types of coffee. Finally, there were no statistically significant or consistent differences between cases and controls in the intake of artificial sweeteners and tea.
这项饮食研究基于1977年至1986年间在夏威夷确诊的195例男性和66例女性下尿路癌症病例。每个病例均按照性别、年龄和种族(白种人或日本人)与2名基于人群的对照进行匹配。女性维生素C摄入量增加时风险降低(p = 0.03),男性深绿色蔬菜摄入量增加时风险降低(p = 0.02)。按四分位数检查时,摄入量最高四分位数与最低四分位数相比,女性的比值比为0.4,男性为0.6。尽管深绿色蔬菜是类胡萝卜素的一个来源,但总类胡萝卜素、视黄醇和总维生素A的摄入量与两性风险的关联较弱且不一致。仅在女性中,饮用普通研磨咖啡也与风险呈负相关(p = 0.02),但与其他类型的咖啡无关。最后,病例组和对照组在人工甜味剂和茶的摄入量方面没有统计学上显著或一致的差异。