Department of Public Health Sciences, University of California, Davis, California 95616, USA.
Environ Sci Technol. 2010 Apr 1;44(7):2648-53. doi: 10.1021/es903240g.
This study determined the body burden of PBDEs in 100 California children, and evaluated associations with sociodemographic, household, and dietary factors. In national and international comparisons, California dust, breast milk, and human serum samples contain higher concentrations of PBDEs. Higher levels in children suggest exposure pathways depend upon age. Plasma samples were analyzed for PBDEs using GC/MS. Circulating levels of PBDEs were 10-to 1000-fold higher than similar aged populations in Mexico and Europe, 5-times higher than similar aged children across the U.S., and 2- to 10-fold higher than U.S. adults. Increased levels of higher-brominated congeners were associated with the recent purchase of new upholstered furniture or mattresses and consumption of pork. Concentrations of lower-brominated congeners increased with frequency of poultry consumption. Lower maternal education was independently and significantly associated with higher levels of most congeners in the children.
本研究旨在确定 100 名加利福尼亚儿童体内的多溴二苯醚（PBDEs）含量，并评估其与社会人口学、家庭和饮食因素的相关性。在国内外比较中，加利福尼亚的灰尘、母乳和人血清样本中含有更高浓度的 PBDEs。儿童体内含量较高表明，暴露途径取决于年龄。使用气相色谱/质谱法（GC/MS）对血浆样本中的 PBDEs 进行了分析。儿童体内 PBDEs 的循环水平比墨西哥和欧洲同年龄人群高出 10 到 1000 倍，比美国同年龄儿童高出 5 倍，比美国成年人高出 2 到 10 倍。较高溴代同系物水平与最近购买新的有软垫家具或床垫以及食用猪肉有关。低溴代同系物浓度随着禽肉消费频率的增加而增加。母亲的教育程度较低与儿童体内大多数同系物水平升高独立且显著相关。
