Damy Sueli Blanes, Camargo Roberto Souza, Chammas Rober, Figueiredo Luiz Francisco Poli de
Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP.
Rev Assoc Med Bras (1992). 2010 Jan-Feb;56(1):103-11. doi: 10.1590/s0104-42302010000100024.
This study aimed to present the general principles for experiments performed on laboratory animals as required by international and national ethical committees on animal welfare. Compliance to these principles is a prerequisite for publication in international journals. Details of genetic, sanitary and environmental standards, transportation, acclimation, environmental enrichment, appropriate education and training of all those involved in handling of live animals, information management strategy, biossecurity, diet, anesthesia, analgesia, postoperative care and euthanasia for Mus musculus (mice), Rattus norvegicus (rat), Oryctolagus cuniculus (rabbit) and Sus scropha domesticus (pig) combined with well planned biomedical research are fundamental to increase the accuracy, reproducibility and precision of the experimental results.
本研究旨在阐述国际和国家动物福利伦理委员会要求的在实验动物身上进行实验的一般原则。遵守这些原则是在国际期刊上发表文章的前提条件。对于小家鼠（小鼠）、褐家鼠（大鼠）、穴兔（兔子）和家猪（猪），遗传学、卫生和环境标准、运输、适应、环境富集、对所有参与活体动物处理人员的适当教育和培训、信息管理策略、生物安全、饮食、麻醉、镇痛、术后护理和安乐死的详细信息，再结合精心规划的生物医学研究，对于提高实验结果的准确性、可重复性和精确性至关重要。
