Menzies Kara L, Jones Lyndon
FAAO School of Optometry, University of Waterloo, Waterloo, Ontario, Canada.
Optom Vis Sci. 2010 Jun;87(6):387-99. doi: 10.1097/OPX.0b013e3181da863e.
Biomaterials may be defined as artificial materials that can mimic, store, or come into close contact with living biological cells or fluids and are becoming increasingly popular in the medical, biomedical, optometric, dental, and pharmaceutical industries. Within the ophthalmic industry, the best example of a biomaterial is a contact lens, which is worn by approximately 125 million people worldwide. For biomaterials to be biocompatible, they cannot illicit any type of unfavorable response when exposed to the tissue they contact. A characteristic that significantly influences this response is that related to surface wettability, which is often determined by measuring the contact angle of the material. This article reviews the impact of contact angle on the biocompatibility of tissue engineering substrates, blood-contacting devices, dental implants, intraocular lenses, and contact lens materials.
生物材料可定义为能够模拟、储存或与活生物细胞或流体密切接触的人工材料，并且在医学、生物医学、验光、牙科和制药行业中越来越受欢迎。在眼科行业中，生物材料的最佳例子是隐形眼镜，全球约有1.25亿人佩戴。为使生物材料具有生物相容性，当它们暴露于所接触的组织时，不能引发任何类型的不良反应。一个显著影响这种反应的特性是与表面润湿性相关的特性，表面润湿性通常通过测量材料的接触角来确定。本文综述了接触角对组织工程基质、血液接触装置、牙种植体、人工晶状体和隐形眼镜材料生物相容性的影响。
