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基于多位点序列分型和脉冲场凝胶电泳图谱对来自鸡和胃炎或格林-巴利综合征患者的空肠弯曲菌和大肠弯曲菌的分子分型。

Molecular typing of Campylobacter jejuni and C. coli from chickens and patients with gastritis or Guillain-Barré syndrome based on multilocus sequence types and pulsed-field gel electrophoresis patterns.

机构信息

Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, 757 Ichibanchou, Asahimachidori, Niigata 951-8510, Japan.

出版信息

Microbiol Immunol. 2010 Jun;54(6):362-7. doi: 10.1111/j.1348-0421.2010.00222.x.

DOI:10.1111/j.1348-0421.2010.00222.x
PMID:20536735
Abstract

Campylobacter jejuni has recently been noted as the most common cause of bacterial foodborne diseases in Japan. In the present study, we determined ST types of C. jejuni and Campylobacter coli isolated from chickens and patients with enteritis or GBS in Japan and Thailand. C. jejuni from chickens, enteritis, and GBS exhibited divergent ST types and included several novel types in addition to worldwide common types. C. coli from enteritis was also divergent. Novel ST types may represent unidentified native clones in each country. Pulsed-field gel electrophoresis confirmed the above typing and demonstrated long-term persistence and transmission.

摘要

空肠弯曲菌最近被认为是日本最常见的细菌性食源性疾病的病原体。在本研究中,我们确定了来自日本和泰国鸡和肠炎或格林-巴利综合征患者的空肠弯曲菌和结肠弯曲菌的 ST 型。来自鸡、肠炎和 GBS 的空肠弯曲菌表现出不同的 ST 型,除了世界范围内常见的类型外,还包括几种新型。肠炎的结肠弯曲菌也存在差异。新型 ST 型可能代表每个国家未识别的本地克隆。脉冲场凝胶电泳证实了上述分型,并证明了其长期存在和传播。

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