CVderm - German Center for Health Services Research in Dermatology, University Clinics of Hamburg, Hamburg, Germany.
Dermatology. 2010;221(2):154-9. doi: 10.1159/000313825. Epub 2010 Jun 18.
The literature on predictors of health-related quality of life in psoriasis is inconsistent.
To assess potential predictors of quality of life in psoriasis.
In a cross-sectional study involving 130 dermatological practices and outpatient clinics, data of 1,210 patients with psoriasis were collected. Quality of life was evaluated using the Dermatology Life Quality Index. Medical history, clinical and sociodemographic characteristics, therapy and health care features were used as independent variables in a backward multiple regression analysis.
Twelve predictors were included in the model explaining 38% of variance in quality of life. The strongest predictor was daily treatment time (beta = 0.30), followed by patient-defined treatment benefit (beta = -0.18), disease severity (beta = 0.19) and treatment satisfaction (beta = -0.16).
Treatment burden requires special attention when quality of life in psoriasis is to be improved. Since the larger part of variance is left unexplained, further factors predicting quality of life have yet to be detected.
关于预测银屑病患者健康相关生活质量的文献不一致。
评估预测银屑病患者生活质量的潜在因素。
在一项涉及 130 个皮肤科诊所和门诊的横断面研究中，收集了 1210 名银屑病患者的数据。使用皮肤病生活质量指数评估生活质量。病史、临床和社会人口统计学特征、治疗和医疗保健特征作为多元回归分析的自变量。
该模型纳入了 12 个预测因素，解释了生活质量 38%的方差。最强的预测因素是每日治疗时间（β=0.30），其次是患者定义的治疗获益（β=-0.18）、疾病严重程度（β=0.19）和治疗满意度（β=-0.16）。
在改善银屑病患者的生活质量时，需要特别关注治疗负担。由于大部分方差仍未得到解释，因此需要进一步检测预测生活质量的其他因素。
