Augustin M, Krüger K, Radtke M A, Schwippl I, Reich K
Health Economics and Quality of Life Research Group, Department of Dermatology, University Clinics of Hamburg, Hamburg, Germany.
Dermatology. 2008;216(4):366-72. doi: 10.1159/000119415. Epub 2008 Mar 4.
Plaque-type psoriasis produces significant morbidity, has negative effects on patients' health-related quality of life (HRQoL), and represents an economic burden.
The assessment of disease severity, HRQoL and health care in plaque-type psoriasis in everyday German medical practice.
Details of patients with plaque-type psoriasis were recorded by 48 dermatologists in Germany. During the visit, demographic data, medical history, previous and current treatments, occupational impairment, the current state of the disease (measured by the Psoriasis Area and Severity Index; PASI), overall lesion severity, and HRQoL were evaluated.
In total, 1,511 plaque-type psoriasis patients were included. The average PASI score was 12.0. The average Dermatology Life Quality Index score was 8.6. Among the patients with the severest psoriasis (PASI >20), only 45.4% had ever been prescribed systemic treatments.
Psoriasis patients have a reduced HRQoL and are not sufficiently treated in practice. A more widespread use of systemic treatment and the definition of treatment goals are essential to improve the standard of care for psoriasis patients.
斑块状银屑病会导致严重的发病情况，对患者的健康相关生活质量（HRQoL）产生负面影响，并构成经济负担。
在德国日常医疗实践中评估斑块状银屑病的疾病严重程度、健康相关生活质量及医疗保健情况。
德国48名皮肤科医生记录了斑块状银屑病患者的详细信息。就诊期间，对人口统计学数据、病史、既往及当前治疗情况、职业损害、疾病当前状态（通过银屑病面积和严重程度指数；PASI测量）、整体皮损严重程度及健康相关生活质量进行了评估。
共纳入1511例斑块状银屑病患者。平均PASI评分为12.0。平均皮肤病生活质量指数评分为8.6。在银屑病最严重（PASI>20）的患者中，仅有45.4%曾接受过系统治疗。
银屑病患者的健康相关生活质量降低，且在实际治疗中未得到充分治疗。更广泛地使用系统治疗及明确治疗目标对于提高银屑病患者的护理标准至关重要。
