Department of Dermatology, Yonsei-Zium Skin Laser Clinic, Seoul, Korea.
Dermatol Surg. 2010 Sep;36(9):1374-80. doi: 10.1111/j.1524-4725.2010.01643.x. Epub 2010 Jul 9.
Postinflammatory hyperpigmentation (PIH) due to facial acne commonly occurs in Fitzpatrick skin types IV to VI and can have a considerable effect on quality of life. The sequelae in terms of pigmentation are often the main reason for consulting a dermatologist and take precedence over the acne itself.
The purpose of this study was to evaluate a new combined photoacoustic-photothermal low-fluence Q-switched neodymium-doped yttrium aluminum garnet (QSNY) laser in the treatment for facial acne and PIH.
Twenty individuals underwent five weekly full-facial treatments using a QSNY laser at 1,064 nm. Another 20 individuals underwent five weekly facial acne treatments by extraction of comedones, and intralesional injections into severely inflamed papules were performed at each treatment session. Clinical assessment scores were determined 1 and 3 months after the last treatment.
QSNY laser treatments at 1,064 nm were found to be effective at treating PIH and have an additional effect on concomitant acne lesions. The authors have indicated no significant interest with commercial supporters.
面部痤疮引起的炎症后色素沉着(PIH)常见于 Fitzpatrick 皮肤类型 IV 至 VI 型,会对生活质量产生重大影响。色素沉着的后遗症通常是咨询皮肤科医生的主要原因,而且优先于痤疮本身。
本研究旨在评估一种新的联合光声-光热低能量 Q-开关掺钕钇铝石榴石(QSNY)激光对面部痤疮和 PIH 的治疗效果。
20 名患者接受了 5 周的全面部 QSNY 激光治疗,波长为 1064nm。另外 20 名患者接受了 5 周的面部痤疮治疗,每次治疗时都要挤出粉刺,并对严重发炎的丘疹进行皮内注射。末次治疗后 1 个月和 3 个月进行临床评估评分。
1064nm 的 QSNY 激光治疗对 PIH 有效,对同时存在的痤疮病变也有额外的疗效。作者表示没有与商业支持者的重大利益关系。